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GeneQ18050849· pop 5· linked from 813 articles

GATA5

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Also known as GATAS, bB379O24.1, GATA binding protein 5, CHTD5

Transcription factor GATA-5 is a protein that in humans is encoded by the GATA5 gene.

In the Vinony graph

Vinony's link graph records 813 inbound references to GATA5, and connects out to PubMed, human chromosome 20 and homeobox.

It is catalogued under topics including Genes on human chromosome 20 and Transcription factors.

Vinony links it to 5 Wikipedia language editions.

Gene data

GATA5

Name: GATA binding protein 5
Type: protein-coding
Position: 62,463,481–62,476,094 (−)
Aliases: CHTD5, GATAS, bB379O24.1
Ensembl: ENSG00000130700
RefSeq RNA: NM_080473.5, XM_006723699.3, XM_054322987.1, XM_054322988.1
RefSeq protein: NP_536721.1, XP_006723762.1, XP_054178962.1, XP_054178963.1

The protein encoded by this gene is a transcription factor that contains two GATA-type zinc fingers. The encoded protein is known to bind to hepatocyte nuclear factor-1alpha (HNF-1alpha), and this interaction is essential for cooperative activation of the intestinal lactase-phlorizin hydrolase promoter. In other organisms, similar proteins may be involved in the establishment of cardiac smooth muscle cell diversity. [provided by RefSeq, Jul 2008].

Gene Ontology

Biological process

negative regulation of transcription by RNA polymerase II heart induction heart induction aortic valve morphogenesis aortic valve morphogenesis aortic valve morphogenesis endocardial cushion fusion endocardial cushion fusion

Molecular function

transcription cis-regulatory region binding transcription cis-regulatory region binding RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific

Cellular component

chromatin chromatin chromatin nucleus nucleus nucleus nucleoplasm nucleoplasm

Pathways

Hemostasis Factors involved in megakaryocyte development and platelet production

via MyGene.info

Gene · Ensembl

GATA binding protein 5

Symbol: GATA5
Biotype: Protein coding
Organism: Homo sapiens
Location: 20:62,463,481-62,476,094
Strand: Reverse (−)
Assembly: GRCh38

View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Instance of: gene

Show 8 more facts

HomoloGene ID: 32031
found in taxon: Homo sapiens
exact match: identifiers.org/ncbigene/140628
chromosome: human chromosome 20
genomic start: 61038553
genomic end: 62475995
cytogenetic location: 20q13.33
expressed in: fundus

Sources (4)

via Wikidata · CC0

~2 min read

Encyclopedic overview

6 sections

Contents

Function
Role in development
See also
References
Further reading
External links

Transcription factor GATA-5 is a protein that in humans is encoded by the GATA5 gene.

== Function ==

Excerpted from Wikipedia’s “GATA5” article, available under the CC BY-SA 4.0 licence.

Available in 5 languages

via Wikidata sitelinks · CC0

Categories

Genes on human chromosome 20 Transcription factors