GATA4
Sign in to saveAlso known as GATA binding protein 4, ASD2, TACHD, VSD1, TOF
Transcription factor GATA-4 is a protein that in humans is encoded by the GATA4 gene.
In the Vinony graph
Vinony's link graph records 838 inbound references to GATA4, and connects out to PubMed, Ensembl genome database project and homeobox.
It is catalogued under topics including Genes on human chromosome 8 and Transcription factors.
Vinony links it to 7 Wikipedia language editions.
Gene data
GATA4- Name
- GATA binding protein 4
- Type
- protein-coding
- Position
- 11,676,785–11,763,223 (+)
- Aliases
- ASD2, TACHD, TOF, VSD1
- Ensembl
- ENSG00000136574
- RefSeq RNA
- NM_001308093.3, NM_001308094.2, NM_001374273.1, NM_001374274.1, NM_002052.5
- RefSeq protein
- NP_001295022.1, NP_001295023.1, NP_001361202.1, NP_001361203.1, NP_002043.2
This gene encodes a member of the GATA family of zinc-finger transcription factors. Members of this family recognize the GATA motif which is present in the promoters of many genes. This protein is thought to regulate genes involved in embryogenesis and in myocardial differentiation and function, and is necessary for normal testicular development. Mutations in this gene have been associated with cardiac septal defects. Additionally, alterations in gene expression have been associated with several cancer types. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
GATA binding protein 4
- Symbol
- GATA4
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 8:11,676,785-11,763,223
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
- Image
- GATA4.png
Show 8 more facts
- HomoloGene ID
- 1551
- genetic association
- atrial heart septal defect
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/2626
- genomic end
- 11617511
- genomic start
- 11534468
- chromosome
- human chromosome 8
- cytogenetic location
- 8p23.1
via Wikidata · CC0
~4 min read
Encyclopedic overview
8 sectionsContents
- Function
- Atrioventricular valve formation
- Interactions
- Clinical relevance
- See also
- References
- Further reading
- External links
Transcription factor GATA-4 is a protein that in humans is encoded by the GATA4 gene.
== Function ==
Excerpted from Wikipedia’s “GATA4” article, available under the CC BY-SA 4.0 licence.