EIF4B
Sign in to saveAlso known as EIF-4B, PRO1843, eukaryotic translation initiation factor 4B
Eukaryotic translation initiation factor 4B is a protein that in humans is encoded by the EIF4B gene.
Gene data
EIF4B- Name
- eukaryotic translation initiation factor 4B
- Type
- protein-coding
- Position
- 53,006,279–53,042,230 (+)
- Aliases
- EIF-4B, PRO1843
- Ensembl
- ENSG00000063046
- RefSeq RNA
- NM_001300821.3, NM_001330654.2, NM_001417.7, NM_018507.1
- RefSeq protein
- NP_001287750.1, NP_001317583.1, NP_001408.2
Enables RNA binding activity. Predicted to be involved in eukaryotic translation initiation factor 4F complex assembly and formation of translation preinitiation complex. Located in cytosol. Biomarker of autism spectrum disorder and major depressive disorder. [provided by Alliance of Genome Resources, Apr 2022]
Gene Ontology
Biological process
Molecular function
Pathways
RNA transport - Homo sapiens (human)mTOR signaling pathway - Homo sapiens (human)PI3K-Akt signaling pathway - Homo sapiens (human)Proteoglycans in cancer - Homo sapiens (human)Developmental BiologyL13a-mediated translational silencing of Ceruloplasmin expressionSignal TransductionMTOR signallingmTORC1-mediated signallingMetabolism of proteins
via MyGene.info
Gene · Ensembl
eukaryotic translation initiation factor 4B
- Symbol
- EIF4B
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 12:53,006,263-53,042,230
- Strand
- Forward (+)
- Assembly
- GRCh38
View on Ensembl →
via Ensembl · EMBL-EBI
Wikidata facts
- Image
- Protein EIF4B PDB 1wi8.png
Show 5 more facts
- HomoloGene ID
- 83162
- exact match
- identifiers.org/ncbigene/1975
- genomic end
- 53042215
- genomic start
- 53006282
- cytogenetic location
- 12q13.13
Sources (3)
via Wikidata · CC0
~4 min read
Article
6 sectionsContents
- Structure
- Function
- Clinical significance
- See also
- References
- Further reading
Eukaryotic translation initiation factor 4B is a protein that in humans is encoded by the EIF4B gene.
== Structure ==
Connections
translation
Entity
Q180686
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Ensembl genome database project
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protein
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Wikidata
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gene
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chromosome
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mitochondrion
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digital object identifier
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International Standard Serial Number
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cytoplasm
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bibcode
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protein biosynthesis
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human genome
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Q229883
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base pair
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locus
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gene expression
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Online Mendelian Inheritance in Man
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Protein Data Bank
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