EIF4E2

Also known as 4E-LP, 4EHP, EIF4EL3, IF4e, eukaryotic translation initiation factor 4E family member 2, h4EHP

Eukaryotic translation initiation factor 4E type 2 is a protein that in humans is encoded by the EIF4E2 gene. It belongs to the eukaryotic translation initiation factor 4E family.

In the Vinony graph

Vinony's link graph records 208 inbound references to EIF4E2, and connects out to PubMed, translation and human chromosome 2.

It is catalogued under the topic Genes on human chromosome 2.

Vinony links it to 6 Wikipedia language editions.

Gene data

EIF4E2

Name: eukaryotic translation initiation factor 4E family member 2
Type: protein-coding
Position: 232,550,633–232,585,201 (+)
Aliases: 4E-LP, 4EHP, EIF4EL3, IF4e, h4EHP
Ensembl: ENSG00000135930
RefSeq RNA: NM_001276336.2, NM_001276337.2, NM_001282958.2, NM_001330201.2, NM_001330202.2
RefSeq protein: NP_001263265.1, NP_001263266.1, NP_001269887.1, NP_001317130.1, NP_001317131.1

Enables ubiquitin protein ligase binding activity. Involved in positive regulation of miRNA mediated inhibition of translation. Acts upstream of or within negative regulation of translation. Located in P-body. Part of mRNA cap binding activity complex. [provided by Alliance of Genome Resources, Apr 2022]

Pathways

RNA transport - Homo sapiens (human)HIF-1 signaling pathway - Homo sapiens (human)mTOR signaling pathway - Homo sapiens (human)PI3K-Akt signaling pathway - Homo sapiens (human)Longevity regulating pathway - Homo sapiens (human)Insulin signaling pathway - Homo sapiens (human)ISG15 antiviral mechanism Antimicrobial mechanism of IFN-stimulated genes Cytokine Signaling in Immune system Immune System

via MyGene.info

Gene · Ensembl

eukaryotic translation initiation factor 4E family member 2

Symbol: EIF4E2
Biotype: Protein coding
Organism: Homo sapiens
Location: 2:232,550,633-232,585,201
Strand: Forward (+)
Assembly: GRCh38

View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Instance of: gene
Image: Protein EIF4E2 PDB 2jgb.png

Show 8 more facts

HomoloGene ID: 128466
found in taxon: Homo sapiens
exact match: identifiers.org/ncbigene/9470
genomic end: 233448354
genomic start: 232550659
chromosome: human chromosome 2
cytogenetic location: 2q37.1
expressed in: amniotic fluid

Sources (4)

via Wikidata · CC0

~1 min read

Encyclopedic overview

4 sections

Contents

Interactions
References
Further reading
External links

Eukaryotic translation initiation factor 4E type 2 is a protein that in humans is encoded by the EIF4E2 gene. It belongs to the eukaryotic translation initiation factor 4E family.

== Interactions ==

Excerpted from Wikipedia’s “EIF4E2” article, available under the CC BY-SA 4.0 licence.