EIF2B1
Sign in to saveAlso known as EIF2B, EIF2BA, eukaryotic translation initiation factor 2B subunit alpha, EIF2Balpha
Translation initiation factor eIF-2B subunit alpha is a protein that in humans is encoded by the EIF2B1 gene.
Gene data
EIF2B1- Name
- eukaryotic translation initiation factor 2B subunit alpha
- Type
- protein-coding
- Position
- 123,620,406–123,633,766 (−)
- Aliases
- EIF2B, EIF2BA, EIF2Balpha, VWM1
- Ensembl
- ENSG00000111361
- RefSeq RNA
- NM_001414.4
- RefSeq protein
- NP_001405.1
This gene encodes one of five subunits of eukaryotic translation initiation factor 2B (EIF2B), a GTP exchange factor for eukaryotic initiation factor 2 and an essential regulator for protein synthesis. Mutations in this gene and the genes encoding other EIF2B subunits have been associated with leukoencephalopathy with vanishing white matter. [provided by RefSeq, Oct 2009].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
eukaryotic translation initiation factor 2B subunit alpha
- Symbol
- EIF2B1
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 12:123,620,406-123,633,766
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
~1 min read
Encyclopedic overview
3 sectionsContents
- Interactions
- References
- Further reading
Translation initiation factor eIF-2B subunit alpha is a protein that in humans is encoded by the EIF2B1 gene.
== Interactions == EIF2B1 has been shown to interact with EIF2B5.
Excerpted from Wikipedia’s “EIF2B1” article, available under the CC BY-SA 4.0 licence.