EIF2S2
Sign in to saveAlso known as EIF2, EIF2B, EIF2beta, PPP1R67, eIF-2-beta, eukaryotic translation initiation factor 2 subunit beta
Eukaryotic translation initiation factor 2 subunit 2 (eIF2β) is a protein that in humans is encoded by the EIF2S2 gene.
In the Vinony graph
Vinony's link graph records 209 inbound references to EIF2S2, and connects out to PubMed, protein biosynthesis and translation.
It is catalogued under the topic Genes on human chromosome 20.
Vinony links it to 5 Wikipedia language editions.
Gene data
EIF2S2- Name
- eukaryotic translation initiation factor 2 subunit beta
- Type
- protein-coding
- Position
- 34,088,309–34,112,284 (−)
- Aliases
- EIF2, EIF2B, EIF2beta, PPP1R67, eIF-2-beta
- Ensembl
- ENSG00000125977
- RefSeq RNA
- NM_001316363.2, NM_001316364.2, NM_003908.5, XM_017028118.2
- RefSeq protein
- NP_001303292.1, NP_001303293.1, NP_003899.2, XP_016883607.1
Eukaryotic translation initiation factor 2 (EIF-2) functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA and binding to a 40S ribosomal subunit. EIF-2 is composed of three subunits, alpha, beta, and gamma, with the protein encoded by this gene representing the beta subunit. The beta subunit catalyzes the exchange of GDP for GTP, which recycles the EIF-2 complex for another round of initiation. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2015].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
eukaryotic translation initiation factor 2 subunit beta
- Symbol
- EIF2S2
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 20:34,088,309-34,112,284
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 8 more facts
- HomoloGene ID
- 2904
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/8894
- genomic end
- 34112243
- genomic start
- 34088309
- chromosome
- human chromosome 20
- cytogenetic location
- 20q11.22
- expressed in
- triceps brachii muscle
Sources (4)
via Wikidata · CC0
~1 min read
Encyclopedic overview
5 sectionsContents
- Function
- Regulation
- See also
- References
- Further reading
Eukaryotic translation initiation factor 2 subunit 2 (eIF2β) is a protein that in humans is encoded by the EIF2S2 gene.
==Function==
Excerpted from Wikipedia’s “EIF2S2” article, available under the CC BY-SA 4.0 licence.