EIF2B3
Sign in to saveAlso known as EIF-2B, EIF2Bgamma, eukaryotic translation initiation factor 2B subunit gamma
Translation initiation factor eIF-2B subunit gamma is a protein that in humans is encoded by the EIF2B3 gene.
Gene data
EIF2B3- Name
- eukaryotic translation initiation factor 2B subunit gamma
- Type
- protein-coding
- Aliases
- EIF-2B, EIF2Bgamma, VWM3
The protein encoded by this gene is one of the subunits of initiation factor eIF2B, which catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP. It has also been found to function as a cofactor of hepatitis C virus internal ribosome entry site-mediated translation. Mutations in this gene have been associated with leukodystrophy with vanishing white matter. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009].
via MyGene.info
Gene · Ensembl
eukaryotic translation initiation factor 2B subunit gamma
- Symbol
- EIF2B3
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 1:44,850,464-44,986,722
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
Show 5 more facts
- HomoloGene ID
- 7005
- exact match
- identifiers.org/ncbigene/8891
- genomic end
- 45452282
- genomic start
- 45316450
- cytogenetic location
- 1p34.1
Sources (4)
via Wikidata · CC0
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Article
2 sectionsContents
- References
- Further reading
Translation initiation factor eIF-2B subunit gamma is a protein that in humans is encoded by the EIF2B3 gene.
==References==