English

English Deutsch Español Français Italiano Nederlands Português Svenska العربية

GeneQ18033199· pop 5· linked from 206 articles

EIF3H

Sign in to save

Also known as EIF3S3, eIF3-gamma, eIF3-p40, eukaryotic translation initiation factor 3 subunit H

Eukaryotic translation initiation factor 3 subunit H (eIF3h) is a protein that in humans is encoded by the EIF3H gene.

In the Vinony graph

Vinony's link graph records 206 inbound references to EIF3H, and connects out to PubMed, translation and human chromosome 8.

It is catalogued under the topic Genes on human chromosome 8.

Vinony links it to 5 Wikipedia language editions.

Gene data

EIF3H

Name: eukaryotic translation initiation factor 3 subunit H
Type: protein-coding
Position: 116,642,130–116,766,925 (−)
Aliases: EIF3S3, eIF3-gamma, eIF3-p40
Ensembl: ENSG00000147677
RefSeq RNA: NM_003756.3, XM_047422380.1, XM_047422381.1, XM_047422382.1, XM_047422383.1
RefSeq protein: NP_003747.1, XP_047278336.1, XP_047278337.1, XP_047278338.1, XP_047278339.1

Enables deubiquitinase activity. Contributes to translation initiation factor activity. Involved in negative regulation of proteasomal ubiquitin-dependent protein catabolic process and translational initiation. Located in extracellular exosome and membrane. Part of eukaryotic translation initiation factor 3 complex. Implicated in breast cancer; prostate cancer; and prostate carcinoma. Biomarker of prostate cancer. [provided by Alliance of Genome Resources, Apr 2022]

Gene Ontology

Biological process

formation of cytoplasmic translation initiation complex formation of cytoplasmic translation initiation complex cytoplasmic translational initiation translational initiation translational initiation translational initiation translational initiation regulation of translational initiation

Molecular function

RNA binding translation initiation factor activity translation initiation factor activity translation initiation factor activity translation initiation factor activity translation initiation factor activity protein binding peptidase activity

Cellular component

cytoplasm cytosol eukaryotic translation initiation factor 3 complex eukaryotic translation initiation factor 3 complex eukaryotic translation initiation factor 3 complex eukaryotic translation initiation factor 3 complex membrane eukaryotic 43S preinitiation complex

Pathways

RNA transport - Homo sapiens (human)Measles - Homo sapiens (human)Antimicrobial mechanism of IFN-stimulated genes Cytokine Signaling in Immune system L13a-mediated translational silencing of Ceruloplasmin expression Immune System Metabolism of proteins Eukaryotic Translation Initiation Translation initiation complex formation Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S

via MyGene.info

Gene · Ensembl

eukaryotic translation initiation factor 3 subunit H

Symbol: EIF3H
Biotype: Protein coding
Organism: Homo sapiens
Location: 8:116,642,130-116,766,925
Strand: Reverse (−)
Assembly: GRCh38

View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Instance of: gene

Show 7 more facts

HomoloGene ID: 2785
exact match: identifiers.org/ncbigene/8667
found in taxon: Homo sapiens
genomic end: 117779164
genomic start: 117654369
chromosome: human chromosome 8
cytogenetic location: 8q23.3-q24.11

Sources (4)

via Wikidata · CC0

~1 min read

Encyclopedic overview

5 sections

Contents

Interactions
See also
References
Further reading
External links

Eukaryotic translation initiation factor 3 subunit H (eIF3h) is a protein that in humans is encoded by the EIF3H gene.

== Interactions ==

Excerpted from Wikipedia’s “EIF3H” article, available under the CC BY-SA 4.0 licence.

Available in 5 languages

via Wikidata sitelinks · CC0

Categories

Genes on human chromosome 8