EIF4A3

Name

eukaryotic translation initiation factor 4A3

Type

protein-coding

Position

80,132,700–80,147,151 (−)

Aliases

DDX48, Fal1, MUK34, NMP265, NUK34, RCPS, eIF-4A-III, eIF4A-III, eIF4AIII

Ensembl

ENSG00000141543

RefSeq RNA

NM_001411099.1, NM_014740.4

RefSeq protein

NP_001398028.1, NP_055555.1

This gene encodes a member of the DEAD box protein family. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. The protein encoded by this gene is a nuclear matrix protein. Its amino acid sequence is highly similar to the amino acid sequences of the translation initiation factors eIF4AI and eIF4AII, two other members of the DEAD box protein family. [provided by RefSeq, Jul 2008].

via MyGene.info

Gene · Ensembl

eukaryotic translation initiation factor 4A3

Symbol

EIF4A3

Biotype

Protein coding

Organism

Homo sapiens

Location

17:80,132,700-80,147,151

Strand

Reverse (−)

Assembly

GRCh38

Wikidata facts

Instance of

gene

Image

Protein EIF4A3 PDB 2hxy.png

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