oxprenolol

Also known as TRO390, BA-39089

Oxprenolol, sold under the brand name Trasicor among others, is a non-selective beta blocker with some intrinsic sympathomimetic activity. It is used for the treatment of angina pectoris, abnormal heart rhythms, and high blood pressure.

Chemical data

Formula: C15H23NO3
Molecular weight: 265.35 g/mol
IUPAC name: 1-(propan-2-ylamino)-3-(2-prop-2-enoxyphenoxy)propan-2-ol
SMILES: CC(C)NCC(COC1=CC=CC=C1OCC=C)O
InChIKey: CEMAWMOMDPGJMB-UHFFFAOYSA-N
XLogP: 2.1
Polar surface area: 50.7 Å²
H-bond donors: 2
H-bond acceptors: 4
Formal charge: 0

via PubChem

Research

1,351 papers

Oxprenolol in clinical practice.The American journal of cardiology · 1983
Oxprenolol: clinical pharmacology, pharmacokinetics, and pharmacodynamics.The American journal of cardiology · 1983
Fatal oxprenolol poisoning.British medical journal · 1977
Oxprenolol hydrochloride: pharmacology, pharmacokinetics, adverse effects and clinical efficacy.Pharmacotherapy · 1983
The atypical β-blocker S-oxprenolol reduces cachexia and improves survival in a rat cancer cachexia model.Journal of cachexia, sarcopenia and muscle · 2023

via PubMed

~2 min read

Encyclopedic overview

10 sections

Contents

Medical uses
Contraindications
Pharmacology
Pharmacodynamics
Pharmacokinetics
Chemistry
Stereochemistry
Society and culture
Brand names
References

==Medical uses== Oxprenolol is used in the treatment of angina pectoris, abnormal heart rhythms, and high blood pressure.

Excerpted from Wikipedia’s “oxprenolol” article, available under the CC BY-SA 4.0 licence.

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