PCBP4

Also known as CBP, LIP4, MCG10, poly(rC) binding protein 4

Poly(rC)-binding protein 4 is a protein that in humans is encoded by the PCBP4 gene.

Gene data

PCBP4

Name: poly(rC) binding protein 4
Type: protein-coding
Aliases: CBP, LIP4, MCG10

This gene encodes a member of the KH-domain protein subfamily. Proteins of this subfamily, also referred to as alpha-CPs, bind to RNA with a specificity for C-rich pyrimidine regions. Alpha-CPs play important roles in post-transcriptional activities and have different cellular distributions. This gene is induced by the p53 tumor suppressor, and the encoded protein can suppress cell proliferation by inducing apoptosis and cell cycle arrest in G(2)-M. This gene's protein is found in the cytoplasm, yet it lacks the nuclear localization signals found in other subfamily members. Multiple alternatively spliced transcript variants have been described, but the full-length nature for only some has been determined. [provided by RefSeq, Jul 2008].

via MyGene.info

Gene · Ensembl

poly(rC) binding protein 4

Symbol: PCBP4
Biotype: Protein coding
Organism: Homo sapiens
Location: 3:51,957,448-51,974,630
Strand: Reverse (−)
Assembly: GRCh38

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via Ensembl · EMBL-EBI

Wikidata facts

Show 5 more facts

HomoloGene ID: 56926
exact match: identifiers.org/ncbigene/57060
genomic end: 52002426
genomic start: 51991470
cytogenetic location: 3p21.2

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Poly(rC)-binding protein 4 is a protein that in humans is encoded by the PCBP4 gene.

This gene encodes a member of the KH domain protein subfamily. Proteins of this subfamily, also referred to as alpha-CPs, bind to RNA with a specificity for C-rich pyrimidine regions. Alpha-CPs play important roles in post-transcriptional activities and have different cellular distributions. This gene is induced by the p53 tumor suppressor, and the encoded protein can suppress cell proliferation by inducing apoptosis and cell cycle arrest in G(2)-M. This gene's protein is found in the cytoplasm, yet it lacks the nuclear localization signals found in other subfamily members. Multiple alternatively spliced transcript variants have been described, but the full-length nature for only some has been determined.