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perzinfotel
Sign in to savePerzinfotel (EAA-090) is a drug which acts as a potent NMDA antagonist. It has neuroprotective effects and has been investigated for the treatment of stroke, but lacks analgesic effects. Nevertheless, it shows a good safety profile compared to older drugs, although further development of this drug has been discontinued.
In the Vinony graph
Within Vinony's link graph, perzinfotel is referenced by 330 other articles, and connects out to pentamidine, 1-aminocyclopropanecarboxylic acid and racemorphan.
Vinony files it under Cyclobutenes, Dissociative drugs and Drugboxes which contain changes to verified fields.
Its subject is documented across 6 Wikipedia language editions.
Chemical data
- Formula
- C9H13N2O5P
- Molecular weight
- 260.18 g/mol
- IUPAC name
- 2-(8,9-dioxo-2,6-diazabicyclo[5.2.0]non-1(7)-en-2-yl)ethylphosphonic acid
- SMILES
- C1CNC2=C(C(=O)C2=O)N(C1)CCP(=O)(O)O
- InChIKey
- BDABGOLMYNHHTR-UHFFFAOYSA-N
- XLogP
- -1.6
- Polar surface area
- 107 Ų
- H-bond donors
- 3
- H-bond acceptors
- 7
- Formal charge
- 0
via PubChem
Wikidata facts
- Subclass of
- chemical compound
- Has part
- hydrogen
- Mass
- 260.056
Show 3 more facts
- chemical formula
- C₉H₁₃N₂O₅P
- canonical SMILES
- C1CNC2=C(C(=O)C2=O)N(C1)CCP(=O)(O)O
- Commons category
- Perzinfotel
Sources (2)
via Wikidata · CC0
~1 min read
Encyclopedic overview
1 sectionsContents
- References
Perzinfotel (EAA-090) is a drug which acts as a potent NMDA antagonist. It has neuroprotective effects and has been investigated for the treatment of stroke, but lacks analgesic effects. Nevertheless, it shows a good safety profile compared to older drugs, although further development of this drug has been discontinued.
Prodrugs were developed since the oral bioavailability of perzinfotel is only around 3-5%.
Excerpted from Wikipedia’s “perzinfotel” article, available under the CC BY-SA 4.0 licence.