Structure via PubChem · Public domain (PubChem)
phendimetrazine
Sign in to savePhendimetrazine, sold under the brand name Bontril among others, is a stimulant medication of the morpholine chemical class used as an appetite suppressant.
In the Vinony graph
Vinony's link graph records 1,544 inbound references to phendimetrazine, and connects out to amphetamines, phenethylamine and N-methyl-1-(3,4-methylenedioxyphenyl)-2-butanamine.
It is catalogued under topics including Anorectics, Anti-obesity drugs and Beta-Hydroxyamphetamines.
Vinony links it to 13 Wikipedia language editions.
Chemical data
- Formula
- C12H17NO
- Molecular weight
- 191.27 g/mol
- IUPAC name
- (2S,3S)-3,4-dimethyl-2-phenylmorpholine
- SMILES
- C[C@H]1[C@@H](OCCN1C)C2=CC=CC=C2
- InChIKey
- MFOCDFTXLCYLKU-CMPLNLGQSA-N
- XLogP
- 1.9
- Polar surface area
- 12.5 Ų
- H-bond donors
- 0
- H-bond acceptors
- 2
- Formal charge
- 0
via PubChem
Research
117 papers- Cocaine-like discriminative stimulus effects of phendimetrazine and phenmetrazine in rats.Behavioural pharmacology · 2016
- Influence of phendimetrazine maintenance on the reinforcing, subjective, performance, and physiological effects of intranasal cocaine.Psychopharmacology · 2019
- Safety and tolerability of intranasal cocaine during phendimetrazine maintenance.Psychopharmacology · 2016
- Abuse Potential of Oral Phendimetrazine in Cocaine-dependent Individuals: Implications for Agonist-like Replacement Therapy.Journal of addiction medicine · 2016
- Pharmacotherapy for obesity.Journal of menopausal medicine · 2014
via PubMed
Wikidata facts
- Mass
- 191.131014
- Has use
- medication
Show 7 more facts
- chemical formula
- C₁₂H₁₇NO
- subject has role
- stimulant
- significant drug interaction
- tranylcypromine
- medical condition treated
- obesity
- canonical SMILES
- CC1C(OCCN1C)C2=CC=CC=C2
- Commons category
- Phendimetrazine
- isomeric SMILES
- C[C@H]1[C@@H](OCCN1C)C2=CC=CC=C2
Sources (2)
via Wikidata · CC0
~3 min read
Encyclopedic overview
6 sectionsContents
- Pharmacology
- Legality
- Synthesis
- Society and culture
- Brand names
- References
Phendimetrazine, sold under the brand name Bontril among others, is a stimulant medication of the morpholine chemical class used as an appetite suppressant.
== Pharmacology == thumb|left|Phendimetrazine tablets and capsules Phendimetrazine functions as a prodrug of phenmetrazine; approximately 30 percent of an oral dose is converted into it. Phendimetrazine can essentially be thought of as an extended-release formulation of phenmetrazine with less potential for abuse. Phendimetrazine is an anorectic drug which acts as a norepinephrine-dopamine releasing agent (NDRA).
Excerpted from Wikipedia’s “phendimetrazine” article, available under the CC BY-SA 4.0 licence.