phenmetrazine
Sign in to saveAlso known as 2-phenyl-3-methylmorpholine
Phenmetrazine, sold under the brand name Preludin among others, is a stimulant drug first synthesized in 1952 and originally used as an appetite suppressant, but withdrawn from the market in the 1980s due to widespread misuse. It was initially replaced by its analogue phendimetrazine (under the brand name Prelu-2) which functions as a prodrug to phenmetrazine, but now it is rarely prescribed, due to concerns of misuse and addiction. Chemically, phenmetrazine is a substituted amphetamine containing a morpholine ring or a substituted phenylmorpholine.
Key facts
- Drug.Verifiedfields
- verified
- Drug.Watchedfields
- verified
- Drug.verifiedrevid
- 464200421
- Drug.image
- Phenmetrazine.svg
- Drug.image_class
- skin-invert-image
- Drug.width
- 175px
- Drug.tradename
- Preludin, others
- Drug.routes_of_administration
- By mouth, Intravenous, Vaporized, Insufflated, Suppository
- Drug.class
- Norepinephrine–dopamine releasing agent; Psychostimulant; Appetite suppressant
- Drug.ATC_prefix
- None
- Drug.legal_AU
- S8
- Drug.legal_BR
- A3
- Drug.legal_CA
- Schedule IV
- Drug.legal_DE
- Anlage II
- Drug.legal_UK
- Class B
- Drug.legal_US
- Schedule II
- Drug.legal_UN
- P II
- Drug.legal_status
- SE: Förteckning II
via Wikipedia infobox
Research
539 papers- Phenmetrazine psychosis.British medical journal · 1968
- Phenmetrazine psychosis.British medical journal · 1968
- [Narcolepsy].Deutsche medizinische Wochenschrift (1946) · 1990
- Phenmetrazine psychoses.Polish medical journal · 1971
- Cocaine-like discriminative stimulus effects of phendimetrazine and phenmetrazine in rats.Behavioural pharmacology · 2016
via PubMed
~9 min read
Encyclopedic overview
13 sectionsContents
- Medical uses
- Pharmacology
- Pharmacodynamics
- Pharmacokinetics
- Chemistry
- Synthesis
- History
- Society and culture
- Names
- Availability
- Legal status
- Recreational use
- References
Phenmetrazine, sold under the brand name Preludin among others, is a stimulant drug first synthesized in 1952 and originally used as an appetite suppressant, but withdrawn from the market in the 1980s due to widespread misuse. It was initially replaced by its analogue phendimetrazine (under the brand name Prelu-2) which functions as a prodrug to phenmetrazine, but now it is rarely prescribed, due to concerns of misuse and addiction. Chemically, phenmetrazine is a substituted amphetamine containing a morpholine ring or a substituted phenylmorpholine.
==Medical uses== Phenmetrazine has been used as an appetite suppressant for purposes of weight loss. It was used therapeutically for this indication at a dosage of 25mg two or three times per day (or 50–75mg/day total) in adults. Phenmetrazine has been found to produce similar weight loss to dextroamphetamine in people with obesity.
Excerpted from Wikipedia’s “phenmetrazine” article, available under the CC BY-SA 4.0 licence.