phenoperidine

Phenoperidine (Operidine or Lealgin), is an opioid analgesic which is structurally related to pethidine and is used clinically as a general anesthetic.

Chemical data

Formula: C23H29NO3
Molecular weight: 367.5 g/mol
IUPAC name: ethyl 1-(3-hydroxy-3-phenylpropyl)-4-phenylpiperidine-4-carboxylate

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Drug data · ChEMBL

Max clinical phase: Phase 2
Molecule type: Small molecule

via ChEMBL · EBI

Research

264 papers

Effect of antacids on the plasma concentration of phenoperidine.British journal of anaesthesia · 1983
[Analgesics. 32].Pharmazeutische Praxis · 1969
Pharmacokinetics of phenoperidine.British journal of anaesthesia · 1986
Phenoperidine in anaesthesia of respiratory cripples.Acta anaesthesiologica Scandinavica. Supplementum · 1966
Comparative study of cardiovascular, neurological and metabolic side effects of 8 narcotics in dogs. Pethidine, piritramide, morphine, phenoperidine, fentanyl, R 39 209, sufentanil, R 34 995. I. Comparative study on the acute toxicity and hemodynamic effects of the narcotics in high and massive doses in curarised and mechanically ventilated dogs.Acta anaesthesiologica Belgica · 1979

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Wikidata facts

Mass: 367.215

Show 2 more facts

chemical formula: C₂₃H₂₉NO₃
canonical SMILES: CCOC(=O)C1(CCN(CC1)CCC(C2=CC=CC=C2)O)C3=CC=CC=C3

Sources (2)

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Article

7 sections

Contents

Medical use
Pharmacology
History and Synthesis
Historical uses
Regulations
References
Further reading

Phenoperidine (Operidine or Lealgin), is an opioid analgesic which is structurally related to pethidine and is used clinically as a general anesthetic.

==Medical use== Phenoperidine is an opioid pain killer—a narcotic analgesic.