Structure via PubChem · Public domain (PubChem)
フォレドリン
Sign in to savePholedrine, also known as '4-hydroxy-N-methylamphetamine and sold under the brand names Paredrinol, Pulsotyl, and Veritol' among others, is a sympathomimetic drug used in topical eye drops to dilate the pupil. It can be used to diagnose Horner's syndrome.
Chemical data
- Formula
- C10H15NO
- Molecular weight
- 165.23 g/mol
- IUPAC name
- 4-[2-(methylamino)propyl]phenol
- SMILES
- CC(CC1=CC=C(C=C1)O)NC
- InChIKey
- SBUQZKJEOOQSBV-UHFFFAOYSA-N
- XLogP
- 1.7
- Polar surface area
- 32.3 Ų
- H-bond donors
- 2
- H-bond acceptors
- 2
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Phase 2
- Molecule type
- Small molecule
via ChEMBL · EBI
Research
151 papers- Pholedrine is a marker of direct disposal of methamphetamine.The Science of the total environment · 2021
- Teratogenic potential of pholedrine: a sympathomimetic vasoconstrictive drug - a population-based case-control study.Congenital anomalies · 2010
- Pholedrine: a substitute for hydroxyamphetamine as a diagnostic eyedrop test in Horner's syndrome.Journal of neurology, neurosurgery, and psychiatry · 1995
- [Pholedrine for determining the site of Horner syndrome].Klinische Monatsblatter fur Augenheilkunde · 1994
- Interaction of the indirectly acting topical sympathomimetics cocaine and pholedrine.German journal of ophthalmology · 1996
via PubMed
Wikidata facts
- Mass
- 165.115
Show 3 more facts
- canonical SMILES
- CC(CC1=CC=C(C=C1)O)NC
- chemical formula
- C₁₀H₁₅NO
- subject has role
- stimulant
Sources (2)
via Wikidata · CC0
Article · 日本語
フォレドリン（または ホレドリン、Pholedrine）または4-ヒドロキシ-N-メチルアンフェタミン(4-hydroxy-N-methylamphetamine、4-HMA)は、交感神経系を刺激する薬物である。パレドリノール(Paredrinol)、プルソチル(Pulsotyl)、ヴェリトール(Veritol)とも言う。瞳孔を拡張させることを目的として目薬に用いられる。また、ホルネル症候群の診断にも用いられる。
Abstract from DBpedia / Wikipedia · CC BY-SA