polygodial

Also known as (-)-polygodial, poligodial, tadeonal

Polygodial a is chemical compound found in dorrigo pepper, mountain pepper, horopito, canelo, paracress, water-pepper, and Dendrodoris limbata.

Research

166 papers

Polygodial, a drimane sesquiterpenoid dialdehyde purified from Drimys winteri, inhibits voltage-gated sodium channels.Natural product research · 2022
Sesquiterpene Polygodial from Drimys brasiliensis (Winteraceae) Down-Regulates Implant-Induced Inflammation and Fibrogenesis in Mice.Journal of natural products · 2020
Antifungal mechanism of polygodial.Journal of agricultural and food chemistry · 2001
Polygodial, an antifungal potentiator.Journal of natural products · 1988
Polygodial, a Sesquiterpene Dialdehyde, Activates Apoptotic Signaling in Castration-Resistant Prostate Cancer Cell Lines by Inducing Oxidative Stress.Cancers · 2022

via PubMed

Wikidata facts

Mass: 234.162

Show 3 more facts

chemical formula: C₁₅H₂₂O₂
isomeric SMILES: C[C@]12CCCC([C@@H]1CC=C([C@@H]2C=O)C=O)(C)C
canonical SMILES: CC1(CCCC2(C1CC=C(C2C=O)C=O)C)C

Sources (2)

via Wikidata · CC0

~2 min read

Article

2 sections

Contents

Biological activity
References

Polygodial a is chemical compound found in dorrigo pepper, mountain pepper, horopito, canelo, paracress, water-pepper, and Dendrodoris limbata. It is a drimane-type sesquiterpene dialdehyde with the chemical formula C15H22O2.

Polygodial elicits a warm and pungent flavour. The compound activates the TRPA1 pain receptor in nerve endings in the mouth that mediate the sensation of pungency.