pregabalin
Also known as (S)-pregabalin, CI 1008, Lyrica®, Nervalin®, PD 144723, (S)-3-Isobutyl GABA, 3-Isobutyl GABA, (S)-3-Isobutyl gaba
Pregabalin, sold under the brand names Axalid and Lyrica among others, is an anticonvulsant, analgesic, and anxiolytic amino acid medication used to treat epilepsy, neuropathic pain, fibromyalgia, restless legs syndrome, opioid withdrawal, generalized anxiety disorder (GAD), and postherpetic neuralgia (a type of nerve damage that can result from shingles). Pregabalin also has antiallodynic properties. Its use in epilepsy is as an add-on therapy for partial seizures. When used before surgery, it reduces pain but results in greater sedation and visual disturbances. It is taken by mouth.
Key facts
- Drug.Verifiedfields
- verified
- Drug.Watchedfields
- verified
- Drug.verifiedrevid
- 457473985
- Drug.image
- Pregabalin.svg
- Drug.image_class
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- Drug.width
- 200
- Drug.image2
- Pregabalin ball-and-stick model.png
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- Drug.tradename
- Lyrica, others
- Drug.MedlinePlus
- a605045
- Drug.DailyMedID
- Pregabalin
- Drug.pregnancy_AU
Article
30 sectionsContents
- Medical uses
- Seizures
- Neuropathic pain
- Anxiety disorders
- Generalized anxiety disorder
- Other uses
- Adverse effects
- Withdrawal symptoms
- Pregnancy
- Breathing
- Abuse potential
- Overdose
- Interactions
- Pharmacology
- Mechanism of action
- Pharmacodynamics
- Pharmacokinetics
- Absorption
- Distribution
- Metabolism
- Elimination
- Chemistry
- Synthesis
- History
- Society and culture
- Legal status
- Economics
- Intellectual property
- Brand names
- References
Pregabalin, sold under the brand names Axalid and Lyrica among others, is an anticonvulsant, analgesic, and anxiolytic amino acid medication used to treat epilepsy, neuropathic pain, fibromyalgia, restless legs syndrome, opioid withdrawal, generalized anxiety disorder (GAD), and postherpetic neuralgia (a type of nerve damage that can result from shingles). Pregabalin also has antiallodynic properties. Its use in epilepsy is as an add-on therapy for partial seizures. When used before surgery, it reduces pain but results in greater sedation and visual disturbances. It is taken by mouth.
Common side effects can include headache, dizziness, sleepiness, euphoria, confusion, trouble with memory, poor coordination, dry mouth, problems with vision, and weight gain. Serious side effects may include angioedema, kidney damage, and seizures.