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propylhexedrine
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propylhexedrine

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Propylhexedrine, sold under the brand name Benzedrex among others, is an alkylamine primarily utilized as a topical decongestant. Its main indications are relief of congestion due to colds, allergies, and allergic rhinitis. Propylhexedrine was first used medically in 1949, with the release of Benzedrex by Smith, Kline & French, and it has been used, mainly within the United States, since then.

Key facts

Drug.H
21
Drug.N
1
Drug.Verifiedfields
changed
Drug.Watchedfields
changed
Drug.verifiedrevid
464217507
Drug.drug_name
Propylhexedrine
Drug.IUPAC_name
(±)-1-cyclohexyl-N-methylpropan-2-amine
Drug.image
Propylhexedrine.svg
Drug.image_class
skin-invert-image
Drug.width
200px
Drug.imageL
Propylhex_3d.png
Drug.image_classL
bg-transparent
Drug.widthL
125px
Drug.imageR
Propylhex_3d (R).png
Drug.image_classR
bg-transparent
Drug.widthR
125px
Drug.captionLR
Left: (S)-PropylhexedrineRight: (R)-Propylhexedrine
Drug.tradename
Benzedrex, Obesin, Dristan Inhaler, and others

via Wikipedia infobox

Wikidata facts

Mass
155.1674
Show 4 more facts
chemical formula
C₁₀H₂₁N
World Health Organisation international non-proprietary name
propylhexedrine
canonical SMILES
CC(CC1CCCCC1)NC
Commons category
Propylhexedrine
Sources (2)

via Wikidata · CC0

~15 min read

Article

31 sections
Contents
  • Medical use
  • Contraindications
  • Adverse effects
  • Overdose
  • Interactions
  • Pharmacology
  • Mechanism of action
  • Pharmacokinetics
  • Chemistry
  • Synthesis
  • Detection in bodily fluids
  • History
  • Manufacturing
  • Society and culture
  • Legal status
  • International control
  • Australia
  • Brazil
  • Canada
  • Germany
  • United Kingdom
  • United States
  • Recreational use
  • Economics
  • Brand names
  • Benzedrex inhaler
  • Dristan inhaler
  • Obesin
  • Maliasin
  • Eventin
  • References

Propylhexedrine, sold under the brand name Benzedrex among others, is an alkylamine primarily utilized as a topical decongestant. Its main indications are relief of congestion due to colds, allergies, and allergic rhinitis. Propylhexedrine was first used medically in 1949, with the release of Benzedrex by Smith, Kline & French, and it has been used, mainly within the United States, since then.

==Medical use== Propylhexedrine is used to treat acute nasal congestion related to the common cold, allergies, and hay fever. For nasal congestion, the dosage is listed as four inhalations (two inhalations per nostril) every two hours for adults and children 6–12 years of age. Each inhalation delivers 0.4 to 0.5 mg (400 to 500 μg) in 800 mL of air. Use is not to exceed three days.

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