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Dirlotapide
Sign in to saveDirlotapide is a drug used to treat obesity in dogs. It is manufactured by Pfizer and Zoetis and marketed under the brand name Slentrol.
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 674.25
Show 5 more facts
- chemical formula
- C₄₀H₃₃F₃N₄O₃
- canonical SMILES
- CN1C2=C(C=C(C=C2)NC(=O)C3=CC=CC=C3C4=CC=C(C=C4)C(F)(F)F)C=C1C(=O)NC(C5=CC=CC=C5)C(=O)N(C)CC6=CC=CC=C6
- isomeric SMILES
- CN1C2=C(C=C(C=C2)NC(=O)C3=CC=CC=C3C4=CC=C(C=C4)C(F)(F)F)C=C1C(=O)N[C@@H](C5=CC=CC=C5)C(=O)N(C)CC6=CC=CC=C6
- medical condition treated
- obesity
- Commons category
- Dirlotapide
via Wikidata · CC0
~2 min read
Encyclopedic overview
3 sectionsContents
- Usage
- Regulation and safety
- References
Dirlotapide is a drug used to treat obesity in dogs. It is manufactured by Pfizer and Zoetis and marketed under the brand name Slentrol.
It works as a gut-selective microsomal triglyceride transfer protein (MTTP or MTP) inhibitor. This blocks the assembly and release of lipoproteins into the bloodstream, thereby reducing fat absorption. It also elicits a satiety signal from lipid-filled cells lining the intestine.
Excerpted from Wikipedia’s “Dirlotapide” article, available under the CC BY-SA 4.0 licence.