Structure via PubChem · Public domain (PubChem)
clofibride
Sign in to saveClofibride is a fibrate. Clofibride is a derivative of clofibrate. In the body it is converted into 4-chlorophenoxyisobutyric acid (clofibric acid), which is the true hypolipidemic agent. So clofibride, just like clofibrate is a prodrug of clofibric acid.
Chemical data
- Formula
- C16H22ClNO4
- Molecular weight
- 327.8 g/mol
- IUPAC name
- [4-(dimethylamino)-4-oxobutyl] 2-(4-chlorophenoxy)-2-methylpropanoate
- SMILES
- CC(C)(C(=O)OCCCC(=O)N(C)C)OC1=CC=C(C=C1)Cl
- InChIKey
- CXQGFLBVUNUQIA-UHFFFAOYSA-N
- XLogP
- 2.8
- Polar surface area
- 55.8 Ų
- H-bond donors
- 0
- H-bond acceptors
- 4
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Phase 2
- Molecule type
- Small molecule
- Indications
- cardiovascular disease
via ChEMBL · EBI
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 327.124
Show 2 more facts
- chemical formula
- C₁₆H₂₂ClNO₄
- canonical SMILES
- CC(C)(C(=O)OCCCC(=O)N(C)C)OC1=CC=C(C=C1)Cl
Sources (2)
via Wikidata · CC0
~1 min read
Encyclopedic overview
1 sectionsContents
- References
Clofibride is a fibrate. Clofibride is a derivative of clofibrate. In the body it is converted into 4-chlorophenoxyisobutyric acid (clofibric acid), which is the true hypolipidemic agent. So clofibride, just like clofibrate is a prodrug of clofibric acid.
== References ==
Excerpted from Wikipedia’s “clofibride” article, available under the CC BY-SA 4.0 licence.
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