niceritrol
Sign in to saveNiceritrol is a niacin derivative used as a hypolipidemic agent. It is an ester of pentaerythritol and nicotinic acid, has general properties similar to those of nicotinic acid (Nicotinamide), to which it is slowly hydrolysed. Niceritrol has been used as a lipid regulating drug in hyperlipidaemias and as a vasodilator in the treatment of peripheral vascular disease.
In the Vinony graph
Vinony's link graph records 91 inbound references to niceritrol, and connects out to nicotinic acid, liver and medication.
Vinony files it under Drugboxes which contain changes to verified fields, Drugboxes which contain changes to watched fields and Drugs with no legal status.
Vinony links it to 9 Wikipedia language editions.
Research
69 papers- Dose-dependent effect of niceritrol on plasma lipoprotein-a.Scandinavian journal of clinical and laboratory investigation · 1996
- The effects of combination therapy with niceritrol and pravastatin on hyperlipidaemia.The Journal of international medical research · 2002
- Effect of niceritrol on fibrinolysis and lipoprotein (a) levels in patients with coronary artery disease.Coronary artery disease · 1996
- Effect of niceritrol on lipid metabolism of aorta in atherosclerotic rats.The Tohoku journal of experimental medicine · 1984
- Niceritrol prevents the decrease in red blood cell 2,3-diphosphoglycerate and neuropathy in streptozotocin-induced diabetic rats.Journal of diabetes and its complications · 1995
via PubMed
Wikidata facts
- Mass
- 556.159
Show 2 more facts
- chemical formula
- C₂₉H₂₄N₄O₈
- canonical SMILES
- C1=CC(=CN=C1)C(=O)OCC(COC(=O)C2=CN=CC=C2)(COC(=O)C3=CN=CC=C3)COC(=O)C4=CN=CC=C4
Sources (2)
via Wikidata · CC0
~2 min read
Encyclopedic overview
1 sectionsContents
- References
{{Drugbox | Verifiedfields = changed | Watchedfields = changed | verifiedrevid = 447822020 | IUPAC_name = 3-[(pyridin-3-yl)carbonyloxy]-2,2-bis({[(pyridin-3-yl)carbonyloxy]methyl})propyl pyridine-3-carboxylate | image = Niceritrol.png | image_class = skin-invert-image
| tradename = | Drugs.com = | pregnancy_AU = | pregnancy_US = | pregnancy_category = | legal_AU = | legal_CA = | legal_UK = | legal_US = | legal_status = | routes_of_administration =
Excerpted from Wikipedia’s “niceritrol” article, available under the CC BY-SA 4.0 licence.
Available in 9 languages
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