pitavastatin
Also known as NKS104, itavastatin, NK 104, NK-104
Pitavastatin (usually as a calcium salt) is a member of the blood cholesterol lowering medication class of statins.
Chemical data
- Formula
- C25H24FNO4
- Molecular weight
- 421.5 g/mol
- IUPAC name
- (E,3R,5S)-7-[2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl]-3,5-dihydroxyhept-6-enoic acid
- SMILES
- C1CC1C2=NC3=CC=CC=C3C(=C2/C=C/[C@H](C[C@H](CC(=O)O)O)O)C4=CC=C(C=C4)F
- InChIKey
- VGYFMXBACGZSIL-MCBHFWOFSA-N
- XLogP
- 3.5
- Polar surface area
- 90.7 Ų
- H-bond donors
- 3
- H-bond acceptors
- 6
- Formal charge
- 0
via PubChem
Article
8 sectionsContents
- Medical uses
- Side effects
- Metabolism and interactions
- History
- Society and culture
- Brand names
- Research
- References
Pitavastatin (usually as a calcium salt) is a member of the blood cholesterol lowering medication class of statins.
Pitavastatin is an inhibitor of HMG-CoA reductase, the enzyme that catalyses the first step of cholesterol synthesis.
Connections
Categories
4-Fluorophenyl compoundsBeta hydroxycarboxylic acidsCarboxylic acidsChemical pages without DrugBank identifierCyclopropyl compoundsDiolsDrugboxes which contain changes to verified fieldsDrugboxes which contain changes to watched fieldsDrugs developed by Eli Lilly and CompanyDrugs with non-standard legal statusECHA InfoCard ID from Wikidata