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telmisartan

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EntityQ733186· pop 29· linked from 311 articles

telmisartan

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Also known as BIBR-277SE, Micardis®, Pritor®, 4'-((1,4'-dimethyl-2'-propyl(2,6'-bi-1H-benzimidazol)-1'-yl)methyl)-(1,1'-biphenyl)-2-carboxylic acid, 4'-((4-methyl-6-(1-methyl-2-benzimidazolyl)-2-propyl-1-benzimidazolyl)methyl)-2-biphenylcarboxylic acid, BIBR 277, 4'-[(1,7'-dimethyl-2'-propyl-1H,3'H-2,5'-bibenzimidazol-3'-yl)methyl]biphenyl-2-carboxylic acid, 4'-[(1,4'-dimethyl-2'propyl[2,6'-bi-1H-benzimidazol]-1'-yl)methyl]-[1,1'-biphenyl]-2-carboxylic acid

Telmisartan, sold under the brand name Micardis among others, is a medication used to treat high blood pressure and heart failure. It is a reasonable initial treatment for high blood pressure. It is taken by mouth.

Key facts

Drug.Watchedfields
changed
Drug.verifiedrevid
477861448
Drug.image
Telmisartan.svg
Drug.image_class
skin-invert-image
Drug.width
220
Drug.tradename
Micardis, others
Drug.MedlinePlus
a601249
Drug.DailyMedID
Telmisartan
Drug.pregnancy_AU
D
Drug.pregnancy_category
Not recommended
Drug.routes_of_administration
By mouth
Drug.class
Angiotensin II receptor antagonist
Drug.ATC_prefix
C09
Drug.ATC_suffix
CA07
Drug.legal_AU
S4
Drug.legal_CA
Rx-only
Drug.legal_UK
POM
Drug.legal_US
Rx-only

via Wikipedia infobox

Chemical data

Formula
C33H30N4O2
Molecular weight
514.6 g/mol
IUPAC name
2-[4-[[4-methyl-6-(1-methylbenzimidazol-2-yl)-2-propylbenzimidazol-1-yl]methyl]phenyl]benzoic acid
SMILES
CCCC1=NC2=C(N1CC3=CC=C(C=C3)C4=CC=CC=C4C(=O)O)C=C(C=C2C)C5=NC6=CC=CC=C6N5C
InChIKey
RMMXLENWKUUMAY-UHFFFAOYSA-N
XLogP
6.9
Polar surface area
72.9 Ų
H-bond donors
1
H-bond acceptors
4
Formal charge
0

via PubChem

Research

3,150 papers

via PubMed

Wikidata facts

Mass
514.237
Has use
medication
Show 8 more facts
chemical formula
C₃₃H₃₀N₄O₂
canonical SMILES
CCCC1=NC2=C(C=C(C=C2N1CC3=CC=C(C=C3)C4=CC=CC=C4C(=O)O)C5=NC6=CC=CC=C6N5C)C
World Health Organisation international non-proprietary name
telmisartan
defined daily dose
40
subject has role
antihypertensive drug
significant drug interaction
perindopril
Commons category
Telmisartan
legal status (medicine)
boxed warning
Sources (7)

via Wikidata · CC0

~8 min read

Encyclopedic overview

12 sections
Contents
  • Medical uses
  • Contraindications
  • Side effects
  • Interactions
  • Pharmacology
  • Mechanism of action
  • Pharmacokinetics
  • History
  • Society and culture
  • Research
  • References
  • Further reading

{{Infobox drug | Watchedfields = changed | verifiedrevid = 477861448 | image = Telmisartan.svg | image_class = skin-invert-image | width = 220 | alt =

| pronounce = | tradename = Micardis, others | Drugs.com = | MedlinePlus = a601249 | DailyMedID = Telmisartan | pregnancy_AU = D | pregnancy_AU_comment = | pregnancy_category = Not recommended | routes_of_administration = By mouth | class = Angiotensin II receptor antagonist | ATC_prefix = C09 | ATC_suffix = CA07 | ATC_supplemental =

Excerpted from Wikipedia’s “telmisartan” article, available under the CC BY-SA 4.0 licence.