prothioconazole
Sign in to saveProthioconazole is a synthetic chemical produced primarily for its fungicidal properties. It is a member of the class of compounds triazoles, and possesses a unique toxophore in this class of fungicides. Its effective fungicidal properties can be attributed to its ability to inhibit CYP51A1. This enzyme is required to biosynthesize ergosterol, a key component in the cell membrane of fungi.
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Encyclopedic overview
10 sectionsContents
- Synthesis
- Chemical properties
- Toxicology
- Classification
- Toxicity
- Metabolism in animals
- Metabolism in plants
- Biochemical properties
- Interactions
- References
Prothioconazole is a synthetic chemical produced primarily for its fungicidal properties. It is a member of the class of compounds triazoles, and possesses a unique toxophore in this class of fungicides. Its effective fungicidal properties can be attributed to its ability to inhibit CYP51A1. This enzyme is required to biosynthesize ergosterol, a key component in the cell membrane of fungi.
Prothioconazole was first introduced into the market in 2004 by Bayer CropScience and quickly gained popularity due to its broad spectrum of activity against many fungal diseases of important cereal crops. It is used as a solo product under the trade name Proline, and in various mixtures in many other commercially produced fungicides.
Excerpted from Wikipedia’s “prothioconazole” article, available under the CC BY-SA 4.0 licence.