cefoperazone
Also known as CPZ, (6R,7R)-7-({(2R)-2-[(4-ethyl-2,3-dioxopiperazine-1-carbonyl)amino]-2-(4-hydroxyphenyl)acetyl}amino)-3-[(1-methyltetrazol-5-yl)sulfanylmethyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
Cefoperazone is a third-generation cephalosporin antibiotic, marketed by Pfizer under the name Cefobid. It is one of few cephalosporin antibiotics effective in treating Pseudomonas bacterial infections which are otherwise resistant to these antibiotics.
Chemical data
- Formula
- C25H27N9O8S2
- Molecular weight
- 645.7 g/mol
- IUPAC name
- (6R,7R)-7-[[(2R)-2-[(4-ethyl-2,3-dioxopiperazine-1-carbonyl)amino]-2-(4-hydroxyphenyl)acetyl]amino]-3-[(1-methyltetrazol-5-yl)sulfanylmethyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
- SMILES
- CCN1CCN(C(=O)C1=O)C(=O)N[C@H](C2=CC=C(C=C2)O)C(=O)N[C@H]3[C@@H]4N(C3=O)C(=C(CS4)CSC5=NN=NN5C)C(=O)O
- InChIKey
- GCFBRXLSHGKWDP-XCGNWRKASA-N
- XLogP
- -0.7
- Polar surface area
- 271 Ų
- H-bond donors
- 4
- H-bond acceptors
- 13
- Formal charge
- 0
via PubChem
Research
3,428 papersArticle
3 sectionsContents
- Spectrum of bacterial susceptibility
- Adverse effects
- References
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