Structure via PubChem · Public domain (PubChem)
سودوریدین
Sign in to saveAlso known as Psi-uridine, (1S)-1,4-anhydro-1-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)-D-ribitol, p, 5-(beta-D-ribofuranosyl)uracil, beta-Pseudouridine, beta-delta-Pseudouridine, Pseudouridine C, b-Pseudouridine
Pseudouridine (5-ribosyluracil, abbreviated by the Greek letter psi- Ψ) is an isomer of the nucleoside uridine in which the uracil is attached via a carbon-carbon instead of a nitrogen-carbon glycosidic bond.
Chemical data
- Formula
- C9H12N2O6
- Molecular weight
- 244.2 g/mol
- IUPAC name
- 5-[(2S,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-pyrimidine-2,4-dione
- SMILES
- C1=C(C(=O)NC(=O)N1)[C@H]2[C@@H]([C@@H]([C@H](O2)CO)O)O
- InChIKey
- PTJWIQPHWPFNBW-GBNDHIKLSA-N
- XLogP
- -2.8
- Polar surface area
- 128 Ų
- H-bond donors
- 5
- H-bond acceptors
- 6
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Molecule type
- Small molecule
via ChEMBL · EBI
Research
2,046 papers- Incorporation of pseudouridine into mRNA yields superior nonimmunogenic vector with increased translational capacity and biological stability.Molecular therapy : the journal of the American Society of Gene Therapy · 2008
- RNA pseudouridine modification in plants.Journal of experimental botany · 2023
- Pseudouridine as a novel biomarker in prostate cancer.Urologic oncology · 2021
- Incorporation of pseudouridine into mRNA enhances translation by diminishing PKR activation.Nucleic acids research · 2010
- Pseudouridine Synthase 7 in Cancer: Functions, Mechanisms, and Therapeutic Potential.Cells · 2025
via PubMed
Wikidata facts
- Has part
- carbon
- Mass
- 244.069536
Show 5 more facts
- subject has role
- primary metabolite
- chemical formula
- C₉H₁₂N₂O₆
- canonical SMILES
- C1=C(C(=O)NC(=O)N1)C2C(C(C(O2)CO)O)O
- isomeric SMILES
- C1=C(C(=O)NC(=O)N1)[C@H]2[C@@H]([C@@H]([C@H](O2)CO)O)O
- Commons category
- Pseudouridine
via Wikidata · CC0