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GeneQ18047749· pop 6· linked from 2 articles

Also known as DDA3, FP3214, proline and serine rich coiled-coil 1

Proline/serine-rich coiled-coil protein 1 is a protein that in humans is encoded by the PSRC1 gene.

Gene data

PSRC1
Name
proline and serine rich coiled-coil 1
Type
protein-coding
Aliases
DDA3, FP3214

This gene encodes a proline-rich protein that is a target for regulation by the tumor suppressor protein p53. The encoded protein plays an important role in mitosis by recruiting and regulating microtubule depolymerases that destabalize microtubules. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Apr 2014].

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proline and serine rich coiled-coil 1

Symbol
PSRC1
Biotype
Protein coding
Organism
Homo sapiens
Location
1:109,279,053-109,284,107
Strand
Reverse (−)
Assembly
GRCh38
View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Show 5 more facts
HomoloGene ID
49603
genomic end
109825808
genomic start
109822178
cytogenetic location
1p13.3
Sources (6)

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Article

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Contents
  • References
  • Further reading

Proline/serine-rich coiled-coil protein 1 is a protein that in humans is encoded by the PSRC1 gene.

This gene encodes a proline-rich protein. Studies of the related mouse gene suggest that this gene is regulated by p53 and may participate in p53-mediated growth suppression. Alternatively spliced transcript variants encoding different isoforms have been described.

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