quazepam
Sign in to saveAlso known as SCH-16134
Quazepam, sold under the brand name Doral among others, is a relatively long-acting benzodiazepine derivative drug developed by the Schering Corporation in the 1970s. Quazepam is used for the treatment of insomnia, including sleep induction and sleep maintenance. Quazepam induces impairment of motor function and has relatively (and uniquely) selective hypnotic and anticonvulsant properties with considerably less overdose potential than other benzodiazepines (due to its novel receptor-subtype selectivity). Quazepam is an effective hypnotic which induces and maintains sleep without disruption of
Key facts
- Drug.Verifiedfields
- changed
- Drug.Watchedfields
- changed
- Drug.verifiedrevid
- 464378222
- Drug.image
- Quazepam.svg
- Drug.image_class
- skin-invert-image
- Drug.width
- 199
- Drug.alt
- 2
- Drug.image2
- Quazepam ball-and-stick model.png
- Drug.image_class2
- bg-transparent
- Drug.width2
- 180
- Drug.tradename
- Doral
- Drug.MedlinePlus
- a684001
- Drug.pregnancy_AU
- D
- Drug.legal_CA
- Schedule IV
- Drug.legal_US
- Schedule IV
- Drug.routes_of_administration
- By mouth
- Drug.ATC_prefix
- N05
- Drug.ATC_suffix
- CD10
via Wikipedia infobox
Research
165 papers- Quazepam.2012
- Quazepam.2006
- Reintroduction of quazepam: an update on comparative hypnotic and adverse effects.International clinical psychopharmacology · 2019
- Quazepam: hypnotic efficacy and side effects.Pharmacotherapy · 1990
- Quazepam. A preliminary review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy in insomnia.Drugs · 1988
via PubMed
Wikidata facts
- Mass
- 386.02676
- Has use
- medication
Show 8 more facts
- chemical formula
- C₁₇H₁₁ClF₄N₂S
- World Health Organisation international non-proprietary name
- quazepam
- medical condition treated
- sleep disorder
- canonical SMILES
- C1C(=S)N(C2=C(C=C(C=C2)Cl)C(=N1)C3=CC=CC=C3F)CC(F)(F)F
- Commons category
- Quazepam
- defined daily dose
- 15
- subject has role
- benzodiazepine drug
- legal status (medicine)
- boxed warning
Sources (8)
via Wikidata · CC0
~10 min read
Encyclopedic overview
12 sectionsContents
- Medical uses
- Side effects
- Tolerance and dependence
- Special precautions
- Elderly
- Interactions
- Pharmacology
- Pharmacokinetics
- Mechanism of action
- EEG and sleep
- Drug misuse
- References
Quazepam, sold under the brand name Doral among others, is a relatively long-acting benzodiazepine derivative drug developed by the Schering Corporation in the 1970s. Quazepam is used for the treatment of insomnia, including sleep induction and sleep maintenance. Quazepam induces impairment of motor function and has relatively (and uniquely) selective hypnotic and anticonvulsant properties with considerably less overdose potential than other benzodiazepines (due to its novel receptor-subtype selectivity). Quazepam is an effective hypnotic which induces and maintains sleep without disruption of the sleep architecture.
It was patented in 1970 and came into medical use in 1985.
Excerpted from Wikipedia’s “quazepam” article, available under the CC BY-SA 4.0 licence.