RALBP1

Name

ralA binding protein 1

Type

protein-coding

Position

9,474,991–9,538,114 (+)

Aliases

RIP1, RLIP1, RLIP76

Ensembl

ENSG00000017797

RefSeq RNA

NM_006788.4, XM_047437278.1, XM_047437279.1, XM_047437280.1, XM_047437281.1

RefSeq protein

NP_006779.1, XP_047293234.1, XP_047293235.1, XP_047293236.1, XP_047293237.1

RALBP1 plays a role in receptor-mediated endocytosis and is a downstream effector of the small GTP-binding protein RAL (see RALA; MIM 179550). Small G proteins, such as RAL, have GDP-bound inactive and GTP-bound active forms, which shift from the inactive to the active state through the action of RALGDS (MIM 601619), which in turn is activated by RAS (see HRAS; MIM 190020) (summary by Feig, 2003 [PubMed 12888294]).[supplied by OMIM, Nov 2010].