REV1
Sign in to saveAlso known as REV1L, AIBP80, REV1, DNA directed polymerase, REV1 DNA directed polymerase
DNA repair protein REV1 is a protein that in humans is encoded by the REV1 gene.
Gene data
REV1- Name
- REV1 DNA directed polymerase
- Type
- protein-coding
- Aliases
- AIBP80, REV1L
This gene encodes a protein with similarity to the S. cerevisiae mutagenesis protein Rev1. The Rev1 proteins contain a BRCT domain, which is important in protein-protein interactions. A suggested role for the human Rev1-like protein is as a scaffold that recruits DNA polymerases involved in translesion synthesis (TLS) of damaged DNA. [provided by RefSeq, Mar 2016].
via MyGene.info
Gene · Ensembl
REV1 DNA directed polymerase
- Symbol
- REV1
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 2:99,400,475-99,490,466
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Image
- Protein REV1 PDB 2EBW.png
Show 5 more facts
- HomoloGene ID
- 32309
- exact match
- identifiers.org/ncbigene/51455
- genomic end
- 100106497
- genomic start
- 100016938
- cytogenetic location
- 2q11.2
Sources (3)
via Wikidata · CC0
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4 sectionsContents
- Interactions
- See also
- References
- Further reading
DNA repair protein REV1 is a protein that in humans is encoded by the REV1 gene.
This gene encodes a protein with similarity to the S. cerevisiae mutagenesis protein Rev1. The Rev1 proteins contain a BRCT domain, which is important in protein-protein interactions. A suggested role for the human Rev1-like protein is as a scaffold that recruits DNA polymerases involved in translesion synthesis (TLS) of damaged DNA. Two alternatively spliced transcript variants that encode different proteins have been found.