MAD2L2

Also known as MAD2B, POLZ2, REV7, MAD2 mitotic arrest deficient-like 2 (yeast), mitotic arrest deficient 2 like 2, FANCV

Mitotic spindle assembly checkpoint protein MAD2B is a protein that in humans is encoded by the MAD2L2 gene.

Gene data

MAD2L2

Name: mitotic arrest deficient 2 like 2
Type: protein-coding
Aliases: FANCV, MAD2B, POLZ2, REV7

The protein encoded by this gene is a component of the mitotic spindle assembly checkpoint that prevents the onset of anaphase until all chromosomes are properly aligned at the metaphase plate. The encoded protein, which is similar to MAD2L1, is capable of interacting with ADAM9, ADAM15, REV1, and REV3 proteins. [provided by RefSeq, Jul 2008].

via MyGene.info

Gene · Ensembl

mitotic arrest deficient 2 like 2

Symbol: MAD2L2
Biotype: Protein coding
Organism: Homo sapiens
Location: 1:11,657,230-11,692,605
Strand: Reverse (−)
Assembly: GRCh38

View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Image: Protein MAD2L2 PDB 3ABD.png

Show 5 more facts

HomoloGene ID: 4624
exact match: identifiers.org/ncbigene/10459
genomic end: 11751707
genomic start: 11734537
cytogenetic location: 1p36.22

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Contents

Function
Interactions
References
Further reading

Mitotic spindle assembly checkpoint protein MAD2B is a protein that in humans is encoded by the MAD2L2 gene.

== Function == MAD2L2 is a component of the mitotic spindle assembly checkpoint that prevents the onset of anaphase until all chromosomes are properly aligned at the metaphase plate. MAD2L2 is a homolog of MAD2L1.