rhinosinusitis
Sign in to saveRhinosinusitis is a simultaneous infection of the nasal mucosa (rhinitis) and an infection of the mucosa of the paranasal sinuses (sinusitis). A distinction is made between acute rhinosinusitis and chronic rhinosinusitis.
Research
16,154 papers- Tezepelumab in Adults with Severe Chronic Rhinosinusitis with Nasal Polyps.The New England journal of medicine · 2025
- Biological therapy in chronic rhinosinusitis with nasal polyps.Expert review of clinical immunology · 2025
- Pediatric chronic rhinosinusitis.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2024
- Acute Rhinosinusitis: Rapid Evidence Review.American family physician · 2025
- Rhinosinusitis.The Medical clinics of North America · 2026
via PubMed
Clinical Trials
515 registered- PHASE2COMPLETEDSubcutaneous Omalizumab for Treatment of Chronic Rhinosinusitis With Nasal PolyposisMassachusetts General Hospital · NCT01066104
- RECRUITINGA Study to Investigate the Clinical Outcome and Quality of Life in Chinese Post-operative CRSwNP PatientsAstraZeneca · NCT07446738
- RECRUITINGPropel Drug-Eluting Sinus Implant Family IBUKI CohortMedtronic · NCT07546682
- PHASE3RECRUITINGThe Efficacy and Safety of Raphamin in the Treatment of Acute Rhinosinusitis in Adult PatientsMateria Medica Holding · NCT06901297
- NACOMPLETEDSino-nasal Inhalation of Sodium Chloride 6,0% in Patients With Cystic Fibrosis and Chronic RhinosinusitisUniversity of Jena · NCT01086839
- NAWITHDRAWNEffects of Osteopathic Manipulative Treatment in Chronic Non-allergic RhinosinusitisInstitut des Hautes Etudes Osteopathiques de Nantes · NCT04420052
~3 min read
Article
4 sectionsContents
- Background
- Therapy
- See also
- References
Rhinosinusitis is a simultaneous infection of the nasal mucosa (rhinitis) and an infection of the mucosa of the paranasal sinuses (sinusitis). A distinction is made between acute rhinosinusitis and chronic rhinosinusitis.
== Background == Because sinusitis typically is preceded by an infection of the nasal mucosa, some authors suggest generally replacing the term “sinusitis” with “rhinosinusitis”. The functional unity of the two mucosa speaks in favor of this replacement. A distinction is made between acute and chronic rhinosinusitis. Acute sinusitis lasts a maximum of 12 weeks. The clinical symptoms of acute rhinosinusitis are purulent nasal secretion, nasal obstruction and/or tension headache or feeling of fullness in the facial area. Acute rhinosinusitis can be caused by a viral or bacterial infection – a distinction is not possible during the first days. If the clinical picture follows a two-stage development, it indicates a bacterial rhinosinusitis. Chronic rhinosinusitis lasts more than 12 weeks with no complete recovery. The symptoms of chronic rhinosinusitis are less prominent/pronounced than of acute rhinosinusitis. Chronic rhinosinusitis is characterized/shaped by an impaired nasal inspiration, feelings of pressure and swelling in the facial area, as well as a higher susceptibility to infection.