sarilumab
Sign in to saveAlso known as Kevzara
Sarilumab, sold under the brand name Kevzara, is a human monoclonal antibody medication against the interleukin-6 receptor. Regeneron Pharmaceuticals and Sanofi developed the drug for the treatment of rheumatoid arthritis (RA), for which it received US FDA approval on 22 May 2017 and European Medicines Agency approval on 23 June 2017.
Key facts
- Drug.Verifiedfields
- changed
- Drug.Watchedfields
- changed
- Drug.verifiedrevid
- 464387301
- Drug.type
- mab
- Drug.mab_type
- mab
- Drug.source
- u
- Drug.target
- IL-6R
- Drug.tradename
- Kevzara
- Drug.MedlinePlus
- a617032
- Drug.DailyMedID
- Sarilumab
- Drug.routes_of_administration
- Subcutaneous
- Drug.ATC_prefix
- L04
- Drug.ATC_suffix
- AC14
- Drug.legal_AU
- S4
- Drug.legal_CA
- Rx-only
- Drug.legal_US
- Rx-only
- Drug.legal_EU
- Rx-only
- Drug.bioavailability
- 80%
via Wikipedia infobox
~4 min read
Encyclopedic overview
10 sectionsContents
- Medical uses
- Contraindications
- Side effects
- Clinical trials
- Rheumatoid arthritis
- History
- Research
- COVID-19
- References
- Further reading
Sarilumab, sold under the brand name Kevzara, is a human monoclonal antibody medication against the interleukin-6 receptor. Regeneron Pharmaceuticals and Sanofi developed the drug for the treatment of rheumatoid arthritis (RA), for which it received US FDA approval on 22 May 2017 and European Medicines Agency approval on 23 June 2017.
Development in ankylosing spondylitis has been suspended after the drug failed to show clinical benefit over methotrexate in a phase II trial.
Excerpted from Wikipedia’s “sarilumab” article, available under the CC BY-SA 4.0 licence.