Semax
Sign in to saveAlso known as Met-Glu-His-Phe-Pro-Gly-Pro
Semax (), an abbreviation of "seven amino acids", ) is a medication which is used in Eastern Europe for the treatment of a broad range of conditions like brain trauma but predominantly for its claimed nootropic, neuroprotective, and neurorestorative effects.
Research
229 papers- Semax peptide targets the μ opioid receptor gene Oprm1 to promote deubiquitination and functional recovery after spinal cord injury in female mice.British journal of pharmacology · 2025
- Therapeutic Peptides in Orthopaedics: Applications, Challenges, and Future Directions.Journal of the American Academy of Orthopaedic Surgeons. Global research & reviews · 2026
- Semax, synthetic ACTH(4-10) analogue, attenuates behavioural and neurochemical alterations following early-life fluvoxamine exposure in white rats.Neuropeptides · 2021
- Semax, a Synthetic Regulatory Peptide, Affects Copper-Induced Abeta Aggregation and Amyloid Formation in Artificial Membrane Models.ACS chemical neuroscience · 2022
- Semax, an ACTH(4-10) analogue with nootropic properties, activates dopaminergic and serotoninergic brain systems in rodents.Neurochemical research · 2005
via PubMed
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 813.34796
Show 5 more facts
- canonical SMILES
- CSCCC(C(=O)NC(CCC(=O)O)C(=O)NC(CC1=CN=CN1)C(=O)NC(CC2=CC=CC=C2)C(=O)N3CCCC3C(=O)NCC(=O)N4CCCC4C(=O)O)N
- chemical formula
- C₃₇H₅₁N₉O₁₀S
- isomeric SMILES
- CSCC[C@@H](C(=O)N[C@@H](CCC(=O)O)C(=O)NC(CC1=CN=CN1)C(=O)N[C@@H](CC2=CC=CC=C2)C(=O)N3CCC[C@H]3C(=O)NCC(=O)N4CCC[C@H]4C(=O)O)N
- subject has role
- nootropic
- different from
- semaxanib
Sources (2)
via Wikidata · CC0
~5 min read
Encyclopedic overview
4 sectionsContents
- Medical uses
- Pharmacology
- See also
- References
{{Infobox drug | drug_name = | image = Semax.svg | image_class = skin-invert-image | width = 250px
| tradename = Semax | legal_US = Not FDA approved; unscheduled
Excerpted from Wikipedia’s “Semax” article, available under the CC BY-SA 4.0 licence.