Structure via PubChem · Public domain (PubChem)
sitafloxacin
Sign in to saveSitafloxacin (INN; also called DU-6859a) is a fluoroquinolone antibiotic that shows promise in the treatment of Buruli ulcer. The molecule was identified by Daiichi Sankyo Co., which brought ofloxacin and levofloxacin to the market. Sitafloxacin is currently marketed in Japan by Daiichi Sankyo under the tradename Gracevit.
Chemical data
- Formula
- C19H18ClF2N3O3
- Molecular weight
- 409.8 g/mol
- IUPAC name
- 7-[(7S)-7-amino-5-azaspiro[2.4]heptan-5-yl]-8-chloro-6-fluoro-1-[(1R,2S)-2-fluorocyclopropyl]-4-oxoquinoline-3-carboxylic acid
- SMILES
- C1CC12CN(C[C@H]2N)C3=C(C=C4C(=C3Cl)N(C=C(C4=O)C(=O)O)[C@@H]5C[C@@H]5F)F
- InChIKey
- PNUZDKCDAWUEGK-CYZMBNFOSA-N
- XLogP
- 0.7
- Polar surface area
- 86.9 Ų
- H-bond donors
- 2
- H-bond acceptors
- 8
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Phase 3
- Molecule type
- Small molecule
- Indications
- tuberculosis
via ChEMBL · EBI
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 409.100476
- Has use
- medication
Show 4 more facts
- chemical formula
- C₁₉H₁₈ClF₂N₃O₃
- canonical SMILES
- C1CC12CN(CC2N)C3=C(C=C4C(=C3Cl)N(C=C(C4=O)C(=O)O)C5CC5F)F
- isomeric SMILES
- C1CC12CN(C[C@H]2N)C3=C(C=C4C(=C3Cl)N(C=C(C4=O)C(=O)O)[C@@H]5C[C@@H]5F)F
- Commons category
- Sitafloxacin
Sources (2)
via Wikidata · CC0
~1 min read
Encyclopedic overview
4 sectionsContents
- See also
- References
- Further reading
- External links
Sitafloxacin (INN; also called DU-6859a) is a fluoroquinolone antibiotic that shows promise in the treatment of Buruli ulcer. The molecule was identified by Daiichi Sankyo Co., which brought ofloxacin and levofloxacin to the market. Sitafloxacin is currently marketed in Japan by Daiichi Sankyo under the tradename Gracevit.
== See also == Quinolone
Excerpted from Wikipedia’s “sitafloxacin” article, available under the CC BY-SA 4.0 licence.