SNAI1
Sign in to saveAlso known as SLUGH2, SNA, SNAH, SNAIL, SNAIL1, dJ710H13.1, snail family zinc finger 1, snail family transcriptional repressor 1
Zinc finger protein SNAI1 (sometimes referred to as Snail) is a protein that in humans is encoded by the SNAI1 gene. Snail is a family of transcription factors that promote the repression of the adhesion molecule E-cadherin to regulate epithelial to mesenchymal transition (EMT) during embryonic development.
Gene data
SNAI1- Name
- snail family transcriptional repressor 1
- Type
- protein-coding
- Aliases
- SLUGH2, SNA, SNAH, SNAIL, SNAIL1, dJ710H13.1
The Drosophila embryonic protein snail is a zinc finger transcriptional repressor which downregulates the expression of ectodermal genes within the mesoderm. The nuclear protein encoded by this gene is structurally similar to the Drosophila snail protein, and is also thought to be critical for mesoderm formation in the developing embryo. At least two variants of a similar processed pseudogene have been found on chromosome 2. [provided by RefSeq, Jul 2008].
via MyGene.info
Gene · Ensembl
snail family transcriptional repressor 1
- Symbol
- SNAI1
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 20:49,982,979-49,988,886
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
- Image
- SNAI1.png
Show 7 more facts
- HomoloGene ID
- 4363
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/6615
- genomic end
- 48605423
- genomic start
- 49982980
- chromosome
- human chromosome 20
- cytogenetic location
- 20q13.13
via Wikidata · CC0
~4 min read
Encyclopedic overview
5 sectionsContents
- Function
- Clinical significance
- Interactions
- References
- Further reading
Zinc finger protein SNAI1 (sometimes referred to as Snail) is a protein that in humans is encoded by the SNAI1 gene. Snail is a family of transcription factors that promote the repression of the adhesion molecule E-cadherin to regulate epithelial to mesenchymal transition (EMT) during embryonic development.
== Function ==
Excerpted from Wikipedia’s “SNAI1” article, available under the CC BY-SA 4.0 licence.