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GeneQ14905606· pop 5· linked from 900 articles

Also known as FKHL14, LD, MFH-1, MFH1, forkhead box C2

Forkhead box protein C2 (FOXC2) also known as forkhead-related protein FKHL14 (FKHL14), transcription factor FKH-14, or mesenchyme fork head protein 1 (MFH1) is a protein that in humans is encoded by the FOXC2 gene. FOXC2 is a member of the fork head box (FOX) family of transcription factors.

Gene data

FOXC2
Name
forkhead box C2
Type
protein-coding
Aliases
FKHL14, LD, MFH-1, MFH1

This gene belongs to the forkhead family of transcription factors which is characterized by a distinct DNA-binding forkhead domain. The specific function of this gene has not yet been determined; however, it may play a role in the development of mesenchymal tissues. [provided by RefSeq, Jul 2008].

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Gene · Ensembl

forkhead box C2

Symbol
FOXC2
Biotype
Protein coding
Organism
Homo sapiens
Location
16:86,566,829-86,569,728
Strand
Forward (+)
Assembly
GRCh38
View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Image
PDB 1d5v EBI.jpg
Show 5 more facts
HomoloGene ID
21091
genomic end
86602539
genomic start
86566829
cytogenetic location
16q24.1
Sources (6)

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~2 min read

Article

5 sections
Contents
  • Structure and function
  • Role in disease
  • References
  • Further reading
  • External links

Forkhead box protein C2 (FOXC2) also known as forkhead-related protein FKHL14 (FKHL14), transcription factor FKH-14, or mesenchyme fork head protein 1 (MFH1) is a protein that in humans is encoded by the FOXC2 gene. FOXC2 is a member of the fork head box (FOX) family of transcription factors.

==Structure and function== The protein is 501 amino acids in length. The gene has no introns; the single exon is approximately 1.5kb in size.

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