FOXE3

Also known as FKHL12, FREAC8, forkhead box E3, AAT11, ASGD2, CTRCT34

Forkhead box protein E3 (FOXE3) also known as forkhead-related transcription factor 8 (FREAC-8) is a protein that in humans is encoded by the FOXE3 gene located on the short arm of chromosome 1.

Gene data

FOXE3

Name: forkhead box E3
Type: protein-coding
Position: 47,416,285–47,418,052 (+)
Aliases: AAT11, ASGD2, CATC3, CTRCT34, FKHL12, FREAC8
Ensembl: ENSG00000186790
RefSeq RNA: NM_012186.3
RefSeq protein: NP_036318.1

This intronless gene belongs to the forkhead family of transcription factors, which is characterized by a distinct forkhead domain. The protein encoded functions as a lens-specific transcription factor and plays an important role in vertebrate lens formation. Mutations in this gene are associated with anterior segment mesenchymal dysgenesis and congenital primary aphakia. [provided by RefSeq, Dec 2009].

Gene Ontology

Biological process

eye development lens development in camera-type eye

Article

6 sections

Contents

Function
Development
Clinical significance
See also
References
Further reading

Forkhead box protein E3 (FOXE3) also known as forkhead-related transcription factor 8 (FREAC-8) is a protein that in humans is encoded by the FOXE3 gene located on the short arm of chromosome 1.

== Function ==