SORT1

Name

sortilin 1

Type

protein-coding

Position

109,309,568–109,397,967 (−)

Aliases

Gp95, LDLCQ6, NT3, NTR3

Ensembl

ENSG00000134243

RefSeq RNA

NM_001205228.2, NM_002959.7, XM_005271100.3, XM_005271101.4, XM_054338107.1

RefSeq protein

NP_001192157.1, NP_002950.3, XP_005271157.1, XP_005271158.1, XP_054194082.1

This gene encodes a member of the VPS10-related sortilin family of proteins. The encoded preproprotein is proteolytically processed by furin to generate the mature receptor. This receptor plays a role in the trafficking of different proteins to either the cell surface, or subcellular compartments such as lysosomes and endosomes. Expression levels of this gene may influence the risk of myocardial infarction in human patients. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015].

via MyGene.info

Gene · Ensembl

sortilin 1

Symbol

SORT1

Biotype

Protein coding

Organism

Homo sapiens

Location

1:109,309,568-109,397,967

Strand

Reverse (−)

Assembly

GRCh38

Wikidata facts

Image

Protein SORT1 PDB 3F6K.png

via Wikidata · CC0