GGA1
Sign in to saveAlso known as golgi associated, gamma adaptin ear containing, ARF binding protein 1
ADP-ribosylation factor-binding protein GGA1 is a protein that in humans is encoded by the GGA1 gene.
In the Vinony graph
Within Vinony's link graph, GGA1 is referenced by 8 other articles, and connects out to PubMed, Ensembl genome database project and protein.
It is catalogued under the topic Genes on human chromosome 22.
Its subject is documented across 4 Wikipedia language editions.
Gene data
GGA1- Name
- golgi associated, gamma adaptin ear containing, ARF binding protein 1
- Type
- protein-coding
- Position
- 37,608,474–37,633,564 (+)
- Ensembl
- ENSG00000100083
- RefSeq RNA
- NM_001001560.3, NM_001001561.2, NM_001172687.2, NM_001172688.2, NM_001363771.2
- RefSeq protein
- NP_001001560.1, NP_001166158.1, NP_001166159.1, NP_001350700.1, NP_037497.1
This gene encodes a member of the Golgi-localized, gamma adaptin ear-containing, ARF-binding (GGA) protein family. Members of this family are ubiquitous coat proteins that regulate the trafficking of proteins between the trans-Golgi network and the lysosome. These proteins share an amino-terminal VHS domain which mediates sorting of the mannose 6-phosphate receptors at the trans-Golgi network. They also contain a carboxy-terminal region with homology to the ear domain of gamma-adaptins. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
golgi associated, gamma adaptin ear containing, ARF binding protein 1
- Symbol
- GGA1
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 22:37,608,474-37,633,564
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
- Image
- Protein GGA1 PDB 1j2j.png
Show 9 more facts
- HomoloGene ID
- 39250
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/26088
- genomic start
- 37608725
- chromosome
- human chromosome 22
- genomic end
- 38029571
- cytogenetic location
- 22q13.1
- expressed in
- anterior pituitary
- Commons category
- ADP-ribosylation factor binding protein Gga1
Sources (4)
via Wikidata · CC0
~1 min read
Encyclopedic overview
3 sectionsContents
- Interactions
- References
- Further reading
ADP-ribosylation factor-binding protein GGA1 is a protein that in humans is encoded by the GGA1 gene.
This gene encodes a member of the Golgi-localized, gamma adaptin ear-containing, ARF-binding (GGA) protein family. Members of this family are ubiquitous coat proteins that regulate the trafficking of proteins between the trans-Golgi network and the lysosome. These proteins share an amino-terminal VHS domain which mediates sorting of the mannose 6-phosphate receptors at the trans-Golgi network. They also contain a carboxy-terminal region with homology to the ear domain of gamma-adaptins. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Excerpted from Wikipedia’s “GGA1” article, available under the CC BY-SA 4.0 licence.