Skip to content
GeneQ18053480· pop 5· linked from 484 articles

Also known as PGR27, GPR114, adhesion G protein-coupled receptor G5

G protein-coupled receptor 114 is a protein encoded by the ADGRG5 gene. GPR114 is a member of the adhesion GPCR family. Adhesion GPCRs are characterized by an extended extracellular region often possessing N-terminal protein modules that is linked to a TM7 region via a domain known as the GPCR-Autoproteolysis INducing (GAIN) domain.

Gene data

ADGRG5
Name
adhesion G protein-coupled receptor G5
Type
protein-coding
Aliases
GPR114, PGR27

This gene encodes a member of the adhesion family of G-protein coupled receptors. Members of this family are characterized by long N-termini and multiple functional domains. They may play a role in the immune system as well as in the central nervous system. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016].

via MyGene.info

Gene · Ensembl

adhesion G protein-coupled receptor G5

Symbol
ADGRG5
Biotype
Protein coding
Organism
Homo sapiens
Location
16:57,528,585-57,591,681
Strand
Forward (+)
Assembly
GRCh38
View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Show 5 more facts
HomoloGene ID
17828
genomic end
57625593
genomic start
57542643
cytogenetic location
16q21
Sources (4)

via Wikidata · CC0

~1 min read

Article

4 sections
Contents
  • Tissue distribution
  • Signaling
  • References
  • External links

G protein-coupled receptor 114 is a protein encoded by the ADGRG5 gene. GPR114 is a member of the adhesion GPCR family. Adhesion GPCRs are characterized by an extended extracellular region often possessing N-terminal protein modules that is linked to a TM7 region via a domain known as the GPCR-Autoproteolysis INducing (GAIN) domain.

== Tissue distribution ==

Available in 5 languages

via Wikidata sitelinks · CC0

Connections

Categories