ADGRG5
Sign in to saveAlso known as PGR27, GPR114, adhesion G protein-coupled receptor G5
G protein-coupled receptor 114 is a protein encoded by the ADGRG5 gene. GPR114 is a member of the adhesion GPCR family. Adhesion GPCRs are characterized by an extended extracellular region often possessing N-terminal protein modules that is linked to a TM7 region via a domain known as the GPCR-Autoproteolysis INducing (GAIN) domain.
Gene data
ADGRG5- Name
- adhesion G protein-coupled receptor G5
- Type
- protein-coding
- Position
- 57,528,585–57,591,681 (+)
- Aliases
- GPR114, PGR27
- Ensembl
- ENSG00000159618
- RefSeq RNA
- NM_001304376.3, NM_001318481.2, NM_153837.4, XM_011522949.3, XM_011522950.3
- RefSeq protein
- NP_001291305.1, NP_001305410.1, NP_722579.1, XP_011521251.2, XP_011521252.1
This gene encodes a member of the adhesion family of G-protein coupled receptors. Members of this family are characterized by long N-termini and multiple functional domains. They may play a role in the immune system as well as in the central nervous system. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016].
Gene Ontology
Biological process
Molecular function
via MyGene.info
Gene · Ensembl
adhesion G protein-coupled receptor G5
- Symbol
- ADGRG5
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 16:57,528,585-57,591,681
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
~1 min read
Encyclopedic overview
4 sectionsContents
- Tissue distribution
- Signaling
- References
- External links
G protein-coupled receptor 114 is a protein encoded by the ADGRG5 gene. GPR114 is a member of the adhesion GPCR family. Adhesion GPCRs are characterized by an extended extracellular region often possessing N-terminal protein modules that is linked to a TM7 region via a domain known as the GPCR-Autoproteolysis INducing (GAIN) domain.
== Tissue distribution ==
Excerpted from Wikipedia’s “ADGRG5” article, available under the CC BY-SA 4.0 licence.