LNPEP

Also known as CAP, IRAP, P-LAP, PLAP, leucyl/cystinyl aminopeptidase, leucyl and cystinyl aminopeptidase

protein-coding gene in the species Homo sapiens

In the Vinony graph

Vinony's link graph records 162 inbound references to LNPEP, and connects out to PubMed, Ensembl genome database project and protein.

It sits within the topics EC 3.4.11, Enzymes and Genes on human chromosome 5.

Vinony links it to 6 Wikipedia language editions.

Gene data

LNPEP

Name: leucyl and cystinyl aminopeptidase
Type: protein-coding
Position: 96,934,807–97,037,513 (+)
Aliases: CAP, IRAP, P-LAP, PLAP
Ensembl: ENSG00000113441
RefSeq RNA: NM_005575.3, NM_175920.4, XM_047417177.1, XM_054352582.1
RefSeq protein: NP_005566.2, NP_787116.2, XP_047273133.1, XP_054208557.1

This gene encodes a zinc-dependent aminopeptidase that cleaves vasopressin, oxytocin, lys-bradykinin, met-enkephalin, dynorphin A and other peptide hormones. The protein can be secreted in maternal serum, reside in intracellular vesicles with the insulin-responsive glucose transporter GLUT4, or form a type II integral membrane glycoprotein. The protein catalyzes the final step in the conversion of angiotensinogen to angiotensin IV (AT4) and is also a receptor for AT4. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008].