Also known as CP-22, CP22, SCN, V19, sorcin
protein-coding gene in the species Homo sapiens
In the Vinony graph
Within Vinony's link graph, SRI is referenced by 9 other articles, and connects out to PubMed, human chromosome 7 and Ensembl genome database project.
It sits within the topics Genes on human chromosome 7 and Penta-EF-hand proteins.
Its subject is documented across 5 Wikipedia language editions.
Gene data
SRI- Name
- sorcin
- Type
- protein-coding
- Position
- 88,201,117–88,226,997 (−)
- Aliases
- CP-22, CP22, SCN, V19
- Ensembl
- ENSG00000075142
- RefSeq RNA
- NM_001256891.2, NM_001256892.2, NM_003130.4, NM_198901.2
- RefSeq protein
- NP_001243820.1, NP_001243821.1, NP_003121.1, NP_944490.1
This gene encodes a calcium-binding protein with multiple E-F hand domains that relocates from the cytoplasm to the sarcoplasmic reticulum in response to elevated calcium levels. In addition to regulating intracellular calcium homeostasis it also modulates excitation-contraction coupling in the heart. Alternative splicing results in multiple transcript variants encoding distinct proteins. Multiple pseudogenes exist for this gene. [provided by RefSeq, Mar 2012].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
sorcin
- Symbol
- SRI
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 7:88,201,117-88,226,997
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
- Image
- Protein SRI PDB 1gjy.png
Show 8 more facts
- HomoloGene ID
- 37736
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/6717
- genomic end
- 87856308
- genomic start
- 88205115
- chromosome
- human chromosome 7
- cytogenetic location
- 7q21.12
- expressed in
- nucleus accumbens
Sources (3)
via Wikidata · CC0