TRIO

Also known as ARHGEF23, tgat, trio Rho guanine nucleotide exchange factor, MEBAS, MRD44, MRD63, TRIO gene

protein-coding gene in the species Homo sapiens

Gene data

TRIO

Name: trio Rho guanine nucleotide exchange factor
Type: protein-coding
Position: 14,143,342–14,532,128 (+)
Aliases: ARHGEF23, MEBAS, MRD44, MRD63, tgat
Ensembl: ENSG00000038382
RefSeq RNA: NM_007118.4, NR_134469.2, XM_011514107.3, XM_011514108.2, XM_011514109.4
RefSeq protein: NP_009049.2, XP_011512409.1, XP_011512410.1, XP_011512411.1, XP_011512412.1

This gene encodes a large protein that functions as a GDP to GTP exchange factor. This protein promotes the reorganization of the actin cytoskeleton, thereby playing a role in cell migration and growth. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015].