RYR2
Sign in to saveAlso known as ARVC2, ARVD2, RYR-2, RyR, VTSIP, ryanodine receptor 2, VACRDS
protein-coding gene in the species Homo sapiens
In the Vinony graph
Within Vinony's link graph, RYR2 is referenced by 381 other articles, and connects out to PubMed, Ensembl genome database project and water.
Vinony files it under EF-hand-containing proteins, Genes on human chromosome 1 and Ion channels.
Its subject is documented across 6 Wikipedia language editions.
Gene data
RYR2- Name
- ryanodine receptor 2
- Type
- protein-coding
- Position
- 237,042,184–237,833,988 (+)
- Aliases
- ARVC2, ARVD2, RYR-2, RyR, VACRDS, VTSIP
- Ensembl
- ENSG00000198626
- RefSeq RNA
- NM_001035.3, XM_006711802.4, XM_006711803.4, XM_006711804.4, XM_006711805.4
- RefSeq protein
- NP_001026.2, XP_006711865.1, XP_006711866.1, XP_006711867.1, XP_006711868.1
This gene encodes a ryanodine receptor found in cardiac muscle sarcoplasmic reticulum. The encoded protein is one of the components of a calcium channel, composed of a tetramer of the ryanodine receptor proteins and a tetramer of FK506 binding protein 1B proteins, that supplies calcium to cardiac muscle. Mutations in this gene are associated with stress-induced polymorphic ventricular tachycardia and arrhythmogenic right ventricular dysplasia. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
ryanodine receptor 2
- Symbol
- RYR2
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 1:237,042,184-237,833,988
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
- Image
- RYR2 protein.png
Show 8 more facts
- HomoloGene ID
- 37423
- genetic association
- arrhythmogenic right ventricular cardiomyopathy
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/6262
- genomic end
- 237997288
- genomic start
- 237042184
- chromosome
- human chromosome 1
- cytogenetic location
- 1q43
via Wikidata · CC0