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GeneQ14872994· pop 18· linked from 1,320 articles

Also known as NR3C3, PR, progesterone receptor

protein-coding gene in the species Homo sapiens

Gene data

PGR
Name
progesterone receptor
Type
protein-coding
Position
101,029,624–101,129,813 (−)
Aliases
NR3C3, PR
RefSeq RNA
NM_000926.4, NM_001202474.3, NM_001271161.2, NM_001271162.2, NR_073141.3
RefSeq protein
NP_000917.3, NP_001189403.1, NP_001258090.1, NP_001258091.1, XP_006718921.1

This gene encodes a member of the steroid receptor superfamily. The encoded protein mediates the physiological effects of progesterone, which plays a central role in reproductive events associated with the establishment and maintenance of pregnancy. This gene uses two distinct promotors and translation start sites in the first exon to produce several transcript variants, both protein coding and non-protein coding. Two of the isoforms (A and B) are identical except for an additional 165 amino acids found in the N-terminus of isoform B and mediate their own response genes and physiologic effects with little overlap. [provided by RefSeq, Sep 2015].

via MyGene.info

Gene · Ensembl

progesterone receptor

Symbol
PGR
Biotype
Protein coding
Organism
Homo sapiens
Location
11:101,029,624-101,129,817
Strand
Reverse (−)
Assembly
GRCh38
View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Image
Protein PGR PDB 1a28.png
Show 5 more facts
HomoloGene ID
713
genomic start
100900355
genomic end
101129813
cytogenetic location
11q22.1
Sources (6)

via Wikidata · CC0

Connections

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