NCOR2
Sign in to saveAlso known as CTG26, N-CoR2, SMAP270, SMRT, SMRTE, SMRTE-tau, TNRC14, TRAC
protein-coding gene in the species Homo sapiens
Gene data
NCOR2- Name
- nuclear receptor corepressor 2
- Type
- protein-coding
- Aliases
- CTG26, N-CoR2, SMAP270, SMRT, SMRTE, SMRTE-tau, TNRC14, TRAC-1, TRAC1
This gene encodes a nuclear receptor co-repressor that mediates transcriptional silencing of certain target genes. The encoded protein is a member of a family of thyroid hormone- and retinoic acid receptor-associated co-repressors. This protein acts as part of a multisubunit complex which includes histone deacetylases to modify chromatin structure that prevents basal transcriptional activity of target genes. Aberrant expression of this gene is associated with certain cancers. Alternate splicing results in multiple transcript variants encoding different isoforms.[provided by RefSeq, Apr 2011].
via MyGene.info
Gene · Ensembl
nuclear receptor corepressor 2
- Symbol
- NCOR2
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 12:124,324,407-124,567,647
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Image
- Protein NCOR2 PDB 1xc5.png
Show 5 more facts
- HomoloGene ID
- 31370
- exact match
- identifiers.org/ncbigene/9612
- genomic start
- 124808961
- genomic end
- 125052135
- cytogenetic location
- 12q24.31
Sources (3)
via Wikidata · CC0