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GeneQ18045755· pop 6· linked from 48 articles

Also known as TORC-3, TORC3, CREB regulated transcription coactivator 3

CREB-regulated transcription coactivator 3 is a protein that in humans is encoded by the CRTC3 gene.

Gene data

CRTC3
Name
CREB regulated transcription coactivator 3
Type
protein-coding
Aliases
TORC-3, TORC3

This gene is a member of the CREB regulated transcription coactivator gene family. This family regulates CREB-dependent gene transcription in a phosphorylation-independent manner and may be selective for cAMP-responsive genes. The protein encoded by this gene may induce mitochondrial biogenesis and attenuate catecholamine signaling in adipose tissue. A translocation event between this gene and Notch coactivator mastermind-like gene 2, which results in a fusion protein, has been reported in mucoepidermoid carcinomas. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Jul 2012].

via MyGene.info

Gene · Ensembl

CREB regulated transcription coactivator 3

Symbol
CRTC3
Biotype
Protein coding
Organism
Homo sapiens
Location
15:90,529,881-90,645,345
Strand
Forward (+)
Assembly
GRCh38
View on Ensembl →

via Ensembl · EMBL-EBI

~1 min read

Encyclopedic overview

3 sections
Contents
  • References
  • Further reading
  • External links

CREB-regulated transcription coactivator 3 is a protein that in humans is encoded by the CRTC3 gene.

This gene has been shown to be linked to weight gain.

Excerpted from Wikipedia’s “CRTC3” article, available under the CC BY-SA 4.0 licence.

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