NCOA1
Sign in to saveAlso known as F-SRC-1, KAT13A, RIP160, SRC1, bHLHe42, bHLHe74, nuclear receptor coactivator 1
protein-coding gene in the species Homo sapiens
Gene data
NCOA1- Name
- nuclear receptor coactivator 1
- Type
- protein-coding
- Position
- 24,490,983–24,770,702 (+)
- Aliases
- F-SRC-1, KAT13A, RIP160, SRC1, bHLHe42, bHLHe74
- Ensembl
- ENSG00000084676
- RefSeq RNA
- NM_001362950.1, NM_001362952.1, NM_001362954.1, NM_001362955.1, NM_003743.5
- RefSeq protein
- NP_001349879.1, NP_001349881.1, NP_001349883.1, NP_001349884.1, NP_003734.3
The protein encoded by this gene acts as a transcriptional coactivator for steroid and nuclear hormone receptors. It is a member of the p160/steroid receptor coactivator (SRC) family and like other family members has histone acetyltransferase activity and contains a nuclear localization signal, as well as bHLH and PAS domains. The product of this gene binds nuclear receptors directly and stimulates the transcriptional activities in a hormone-dependent fashion. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
nuclear receptor coactivator 1
- Symbol
- NCOA1
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 2:24,490,983-24,770,702
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
- Image
- Protein NCOA1 PDB 1oj5.png
Show 7 more facts
- HomoloGene ID
- 7859
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/8648
- genomic end
- 24993571
- genomic start
- 24491254
- chromosome
- human chromosome 2
- cytogenetic location
- 2p23.3
via Wikidata · CC0